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single-cell analysis

In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.

In Nature this week: tuatara genome sequence aids in understanding amniote evolution, and more.

In Science this week: chromatin accessibility of microglia during fetal development, and more.

Two companies offering droplet-based single-cell RNA sequencing sample prep, 10x Genomics and 1Cellbio, have launched dual-indexed library preparation products.

Researchers have developed a method, called MemorySeq, to identify genes transcriptome-wide whose expression fluctuations persist for several cell divisions.

The partnership will provide Chinese customers access to the company's IsoLight platform, which enables multiplexed immunoassays at the single-cell level.

In Science this week: researchers recover near-complete smallpox virus genomes from Viking Age-individuals, and more.

In Nature this week: high-quality reference genomes for six bat species, machine-learning approach to identify cell types responding to perturbations in single-cell data, and more.

Codefendant 1Cellbio, an instrument maker that had obtained a co-exclusive license to the patents, said it plans to appeal the court's declaration.

In PNAS this week: genetic evidence for Inca resettlement, analysis of spermatogonial stem cell transcriptomes, and more.

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A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.