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single-cell analysis

In Nature this week: extension to uncultivated virus genome reporting standards, multiplex orthogonal CRISPR-based genome editing approach, and more.

In Nucleic Acids Research this week: updated Aspergillus niger genome annotation, high-throughput sequencing strategy for profiling RNA structure, and more.

The company plans to add 150 to 200 new employees and is quadrupling its space in Pleasanton, California, including a manufacturing site for its microfluidic chips.

The company aims to position its platform as a validation tool for CRISPR-based therapeutics, while continuing to grow in the oncology space.

In a set of new studies, members of an international team mapped gene variation, expression, and regulatory interactions in developing and adult human brains.

The startup plans to use the funds to scale its single-cell DNA analysis technology for blood-based cancer research and expand into CRISPR applications.

The life science research tools firm is offering 8,150,000 shares of its common stock at a price of $6.75 per share for gross proceeds of about $55 million.

The funding is being provided to a number of early-career investigators and collaborative research groups using genomics and other technologies.

In Science this week: single-cell analysis of colorectal cancers finds genome-wide demethylation patterns, and more.

The researchers reported that targeting HDAC4 in the patient-derived neurons appeared to correct the expression of genes that differed in the disease state.

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The US Department of Justice has proposed a rule change to enable DNA to be collected from migrants, the Associated Press reports.

Bernard Fisher, a surgeon who changed how breast cancer is treated, has died at 101, the New York Times reports.

Washington Post columnist writes that she is skeptical about DNA-based diets.

In PNAS this week: recurrent inactivation of DEPDC5 in gastrointestinal stromal tumors, taxonomic reliability of GenBank sequences, and more.