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single-cell analysis

Nucleosome organization appears to follow two principles, according to the researchers' analyses of three different cell types.

Using a new machine-learning approach, researchers from the Sanford Burnham Prebys Medical Discovery Institute analyzed brain cells obtained from mice during neurogenesis.

The Durham, North Carolina-based startup's platform uses an image-based, tissue box-sized tool that cultures cells to capture long-term phenotypic behavior.

The RNA-seq data, for nearly 40,000 cells from the developing mouse brain, can be explored through an interactive online interface called Cell Seek.

The firm will use the funds to advance its high-throughput single-cell analysis platform to analyze heterogeneity in cell populations for research and drug discovery.

The assay will combine the company's CytoSort assay with its automated AIR system for imaging, sorting, and isolating single cells and small colonies.

Fueled by an NIH SBIR grant, analytics firm Cytobank is building out its machine-learning algorithms and adding pipelines to support big-picture research.

The researchers found that the diversity of epithelial cell types was reduced in nasal polyps, which contained few glandular and ciliated cells and were enriched in basal cells.

In Genome Research this week: clonal evolution analysis of acute myeloid leukemia, computational pipeline to examine relationships between bacterial pathogens, and more.

The automated, whole-genome directional genomic hybridization system can measure de novo random, low-frequency, and complex structural variations.

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23andMe is offering early customers re-testing on newer chips for a fee, Wired reports.

He Jiankui is no longer affiliated with Direct Genomics Biotechnology, the single molecule sequencing company he founded, Nikkei Asian Review reports.

Newsweek writes about the hopes for precision medicine in cancer, but also challenges getting it to patients.

In Genome Research this week: genomic architecture of glioblastoma, predictive computational approach to estimate SNP fitness, and more.