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single-cell analysis

The researchers used SC3 to uncover subclones within samples from patients with pre-malignant tumors.

In Nature this week: genotypes linked to hip osteoarthritis, and more.

In Genome Biology this week: genes linked to Hirschsprung disease, structural variant patterns in autism, and more.

Mutation and expression patterns in longitudinal, multifocal, and solitary tumor samples suggest glioblastoma follows a multiverse model of evolution.

In PNAS this week: diatom genetic diversity, microfluidic droplet method for single-cell screening, and more.

The platform, called Seq-Well, is similar to droplet-based approaches but reports increased efficiency.

The firm's full-year 2016 revenues fell 9 percent, also on lower instrument sales.

In Nature this week: genomic influence of cattle on Mongolian yaks, and more.

The NIH is aiming to encourage the development of technologies that can better define cellular heterogeneity, organization, and communication rules.

In Nature this week: studies of prostate cancer aggressiveness, and more.

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Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.

An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.

Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.

In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.