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The researchers found that genes whose transcription in response to an immune challenge diverged across species also varied between single cells.
The team's Pro-Code system enabled simultaneous high-dimensional protein-level phenotyping of hundreds of genes with single-cell resolution.
Using single-cell RNA sequencing and lineage tracing in a mouse model, researchers followed skin stem cell expression patterns in response to skin injury.
In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.
Using a microfluidics-based single-cell isoform RNA-seq approach, researchers clustered cerebellar cells and saw isoforms with cell type-specific expression.
Berkeley Lights markets the Beacon platform — a light-based nanofluidics platform for single-cell selection, characterization, culture, and export.
This Tabula Muris could enable discovery of new cell types, detection of novel gene expression in known cells, and comparison of cell types across organs.
Cells that express genes linked to greater proliferation potential are more likely to downregulate the HIV provirus, according to a new study.
With RNA sequence, expression quantitative trait locus, genome-wide association, and other data, researchers identified disease-related genes in the kidney glomerulus and tubule compartments.
In Science this week: series of reviews about gene modification, and more.
A study of families explores how children transmit SARS-CoV-2, according to the Associated Press.
US Agricultural Research Service scientists have sequenced the genome of the Asian giant hornet.
According to the Economist, pooled testing for COVID-19 could help alleviate strains on testing labs.
In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.