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single-cell analysis

Peking University researchers performed single-cell methylome sequencing on preimplantation cells to examine DNA methylation changes during early development.

The SBIR grant will support the development of the firm's single-cell analysis platform, Tapestri.

Research teams documented mosaic mutations during brain development, as well as rising somatic mutations in aging brains or brains affected by neurodegenerative disease.

Using RNA sequences for thousands of cells, researchers looked at head and neck squamous cell carcinomas and proposed streamlined expression subtypes.

Broad Institute researchers performed RNA-sequencing of 53,000 individual mouse gut epithelial cells to develop and examine expression signatures.

The NIH has awarded $169 million this year to support 110 new projects in the Brain Research through Advancing Innovative Neurotechnologies Initiative.

The funding is being awarded under the auspices of the NIH's BRAIN Initiative Cell Census Network, which aims to establish reference cell atlases of the brain.

The startup will use the funds to commercialize its single-cell analysis platform, which is based in part on droplet microfluidic technology licensed from UCSF.

In Science this week: ancient Neanderthal and human genomes, and more.

In Genome Biology this week: computational approach for analyzing noisy single-cell sequencing profiles, eQTLs of dilated cardiomyopathy, and more.

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The Guardian reports that visa costs could prevent scientists and others from coming to the UK.

The Trump Administration is reconsidering its plan to issue an executive order to require federally funded research to be freely available upon publication, Times Higher Education reports.

Nature News says some preprint repositories may close down due to a lack of funds to cover costs.

In Nature this week: framework for analyzing cancer mutational signatures, treatment resistance in small cell lung cancer followed by increased intratumoral heterogeneity, and more.