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single-cell analysis

Fueled by an NIH SBIR grant, analytics firm Cytobank is building out its machine-learning algorithms and adding pipelines to support big-picture research.

The researchers found that the diversity of epithelial cell types was reduced in nasal polyps, which contained few glandular and ciliated cells and were enriched in basal cells.

In Genome Research this week: clonal evolution analysis of acute myeloid leukemia, computational pipeline to examine relationships between bacterial pathogens, and more.

The automated, whole-genome directional genomic hybridization system can measure de novo random, low-frequency, and complex structural variations.

Cell Count

NPR reports on Human Cell Atlas Consortium's effort to catalog all the different cell types within the human body.

Fluidigm reported that its mass cytometry revenues jumped 32 percent while genomics revenues fell 5 percent year over year.

Single-cell RNA sequencing from mouse trachea and human bronchial epithelial cells unearthed new cell types, including ionocytes enriched for CFTR expression.

The companies will work on applying barcoding technology to single-cell measurements of gene and protein expression and to immune cell profiling.

In PNAS this week: single-cell analysis of blood cells from malaria mosquito vector, genes contributing to high yield in rice, and more.

In Genome Biology this week: processing and analyzing single-cell transcriptome data, computational strategy for designing CRISRP single guide RNAs, and more.

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A South African university has told the Wellcome Sanger Institute to return DNA samples it has from indigenous African communities, The Times reports.

The University of California, Berkeley's Rasmus Nielsen and Xinzhu Wei have retracted their CCR5 gene paper due to a technical artifact.

 

University of Virginia researchers are exploring a genetic risk test to gauge type 1 diabetes risk, NPR reports.

In PNAS this week: researchers compare two high-grade neuroendocrine lung cancers, height among ancient Europeans, and more.