single-cell analysis Ulcerative Colitis Single-Cell Tissue Atlas Gives Insight Into Treatment Response Researchers used a tissue atlas they created to analyze cell types that behave differently with TNF inhibitors treatment. New MGH Technology Taps Microscopy for Single-Cell Sequencing in Spatial Context Premium Image-seq deploys in vivo or in situ imaging to isolate cells from specific tissue locations for single-cell sequencing. Mission Bio, Abiosciences to Develop Analytics For Studying Hematologic Cancers The companies will co-create bioinformatics tools for researchers in China. Proteomics Research Innovation Progressed in 2022 Despite Challenging Business Conditions Premium For proteomics firms, 2022 marked a reversal from an earlier boom, but the field pushed into emerging areas like single-cell, single-molecule, and spatial analyses. T-Cell Subpopulations in Blood May Help Predict Immune Checkpoint Immunotherapy Side Effects Researchers searched for baseline immune cell gene expression signatures and clusters linked to immune-related adverse events on checkpoint blockade immunotherapy. Dec 7, 2022 With $6M in Seed Funding, Swedish Startup Pixelgen Developing Tech to Map Cell Surface Proteins Premium Nov 7, 2022 LevitasBio Raises $35M in Series C Financing Oct 27, 2022 Immunotherapy Response Features Identified in Pancreatic Cancer Microenvironment Oct 4, 2022 Peripheral Neuroblastic Tumor Transcriptomes Point to Transitional Cell State Sep 29, 2022 Integration of Single-Cell RNA-seq, Genomic Data Reveals Cell Types Involved in Genetic Diseases Sep 26, 2022 Regulatory Alterations Overrepresented in Single-Cell Sequence Data From Individual Neurons Sep 23, 2022 Clonal Hematopoiesis Mutation Study in Blood Cells Points to Promotion of Abnormal Blood Cells Aug 30, 2022 S2 Genomics Signs Eisenberg as Israel Distributor Aug 12, 2022 Heart Dysfunction Insights Drawn From Age-Related Cardiomyocyte Mutations Aug 10, 2022 Myocardial Infarction Features Found With Multiomic Molecular Map Aug 4, 2022 Single-Cell Transcriptomics Study Highlights Heart Failure Features Specific to Genotype Jul 28, 2022 NYGC, Karolinska Institute Teams Develop Single-Cell, Multimodal Chromatin Profiling Assays Premium Jul 1, 2022 Single-Cell Analysis of Colorectal Cancer Uncovers Two Epithelial-Cell Based Subtypes Jul 1, 2022 New Single-Cell 'Total' RNA-seq Method Promises More Comprehensive Transcriptome View Premium Jun 22, 2022 Advanced Dilated, Hypertrophic Cardiomyopathy Have Similar Transcriptional Profiles, Study Finds Jun 22, 2022 Single-Cell Proteomics Workflows Developing Rapidly, but Data Analysis Lags Behind Premium Jun 22, 2022 Bio-Techne to Acquire Single-Cell Sorting Firm Namocell Jun 20, 2022 Single-Cell Atlas Reveals Epigenetic, Transcriptomic Changes in Colorectal Cancer Development Jun 17, 2022 Fluent BioSciences, NanoCellect Partner on Single-Cell RNA-seq Workflows Jun 17, 2022 Single-Nucleus Sequencing Analysis Generates Cell Atlas of Ant Superorganism Brains Load More Breaking News New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.