simulation

Two research groups concluded that a one-pulse model for Neanderthal-human mixing does not explain present ancestry patterns in East Asians. 

The algorithm, which was developed by researchers at MIT and validated by a team at Novartis, lets users identify regions on antibodies that are prone to aggregation and then predict mutations to improve the stability of biotherapeutic formulations.

The firm will use its REFS platform to create in silico network models that will be used in simulations that connect drug doses to transcriptional and imaging measurement networks.

There has “been a tremendous shift towards using regulatory, integrative genomic, and kinetic models to understand the biology of drug development [and] disease and using modeling and simulation to predict what the cell is doing.”

Simbios will use physical simulations to understand how drugs work and to study how neural activity ultimately generates movement.

In Print

Premium

Microarray-Related Papers of Note Published in March 2009

The company will use the hospital's cancer clinical and genetic data to develop technologies for glioblastoma diagnostics or treatments.

BioRegion Real Estate

Premium

Pfizer La Jolla Incubator, Chromocell, NJEDA Biotechnology Development Center, Wockhardt USA LLC, Acorda Therapeutics, Eastman Business Park, Qatar Science & Technology Park, and more…

The goal of the project is to build a dynamic model of liver function in rats and humans that will account for effects of genetic variations and other variables, such as patient gender, age, behavioral traits, and environmental factors.

Bioinformatics Briefs

Premium

GeneGo, Entelos, NCI, NIH

Pages

A genome-wide association study highlights a potential role for hair follicles in acne risk, according to New Scientist.

Newsday reports that breast cancer genetic testing guidelines for are out of date and may miss individuals.

In Cell this week: gene editing-based strategy to screen for immune system regulators, ancient plague patterns, and more.

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.