SILAC Study Highlights HeLa Cell Heterogeneity Premium Researchers have found genomic, transcriptomic, proteomic, and phenotypic variation in a comparison of HeLa cells across laboratories and over time. Vanderbilt Team Develops Multi-Omics Platform for Drug Studies Premium In recently published work, the researchers combined RNA-seq, proteomics, and metabolomics to study mechanisms of action of the chemotherapeutic cisplatin. Genentech Scientists Offer Perspective on Proteomics' Evolution Into General Research Tool Premium Writing in MCP, the researchers provided a survey of techniques for biologists interested in using multiplexed quantitative proteomics in their research. Roche Researchers Develop Five-Plex SILAC Method for Quantifying Tyrosine Phosphorylation Dynamics Premium A team of Roche researchers has developed a five-plex SILAC method for quantifying the dynamics of tyrosine phosphorylation. UW-Madison NeuCode Labeling Technique Could Significantly Up Mass Spec Multiplexing for Proteomics Premium This story has been updated to correct an earlier version that identified Steven Gygi as an MIT researcher. He is a researcher at Harvard University. Oct 5, 2012 EMBL Team Combines Click Chemistry and SILAC Mass Spec for Improved Secretome Analysis Premium Jun 17, 2011 Phosphoproteomic Screens Elucidate Feedback Loop Linked to mTOR Inhibitor Resistance Premium Mar 25, 2011 Dundee Scientists Characterize Phosphoproteome of Cytotoxic T Lymphocytes Premium Feb 4, 2011 IFOM Researchers Analyze Effect of EGF-Activation on Protein Ubiquitination Premium Jan 7, 2011 Mann, Uhlen Labs Team Up to Characterize the Proteome and Transcriptome of Three Human Cell Lines Premium May 14, 2010 ISB and OriGene to Collaborate on MRM Database for 5,000 Human Proteins Premium Apr 9, 2010 Mann Lab Develops SILAC-based Approach for Use in Tissue Samples Premium Breaking News Coronary Artery Calcification Contributors, Potential Drug Targets Found in Cross-Ancestry GWAS Max Planck Team Uses Spatial Single-Cell Proteomics Method to Analyze Hepatocyte Heterogeneity US Supreme Court Declines to Hear CareDx Organ Transplant Patent Infringement Case GenomeWeb Top 40 Down 10 Percent in September, Outpacing Decline in Broader Market Natera Submits Signatera Bladder Cancer PMA Module to FDA The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.