Tetraploid African Clawed Frog Genome Shows Unequal Evolution
Researchers took two complementary approaches to assemble the Xenopus laevis genome — whole-genome and long-insert clone-based end sequencing.
CSHL Signs on Hairpin Technologies to Handle Licenses to shRNA Tech
Hairpin will be the exclusive agent for negotiating and executing new license agreements for patents covering the CSHL RNAi technology.
The scientists developed an algorithm to predict shRNA potency and a variant on the canonical microRNA scaffold for the RNAi molecules' construction.
Two members of Memorial Sloan-Kettering Cancer’s high-throughput drug screening facility this month published a study highlighting major shortcomings of RNAi screens, including the failure of such studies to yield reproducible hits.
Amid the continued advancement of biomedical research, it is becoming increasingly apparent that polytherapies — treatment regimens based on multiple drugs that address multiple aspects of a disorder — can offer superior efficacy to monotherapies.
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