Sequencing Technology

The articles focus on test regulation and clinical validation, both in the context of breast cancer risk and general variant assessment.

With more than 100 tumor samples from 92 women with ovarian cancer, researchers searched for mutations related to treatment resistance and relapse.

If CareDx successfully commercializes its cfDNA tests, they would be the firm's first products since AlloMap launched in 2005.

The researchers described in a pre-print publication a modified sample prep process that enabled them to increase read lengths to over 100 kb.

The scientists combined whole-genome shotgun and fosmid pool sequencing, using next-generation sequencing technology from Illumina and BGI's Complete Genomics.

Methods and compositions for DNA fragmentation and tagging by transposases
Multibase delivery for long reads in sequencing by synthesis protocols
Determination of KIR haplotypes associated with disease
Methods and apparatus for detecting molecular interactions using FET arrays
Recombinant polymerases for improved single-molecule sequencing
Methods and apparatus for single-molecule sequencing using energy transfer detection

A Thomson Reuters analysis indicates that the life sciences, rather than the tech sector, are increasingly driving global innovation.

The White House says ethical discussions about genome editing of the human germline are needed.

In Genome Research this week: mitochondrial and nuclear gene fusions in cancer, role of genomic imprinting in tissue-specific gene expression, and more.

Maria Freire from the Foundation for the NIH calls for "politically popular pledges of support" for the NIH to turn into support for increased funding for the agency.

Jun
23
Sponsored by
PerkinElmer

This webinar will demonstrate how automated liquid handling workstations can reduce bottlenecks in library preparation for next-generation sequencing, enabling scientific advances in genomics research that were not possible five years ago.