Sequencing Technology

The group found that a combination of algorithms performs better than any one single algorithm.

A years-long international collaboration to sample the ocean metagenome has published its first findings.

Researchers sequenced a 35,000-year-old wolf specimen from Siberia, using comparative genomics to tease apart the timing of wolf-dog divergence.

Researchers from the Sanger Institute used genomic sequencing to study how somatic mutations build up prior to becoming cancerous. 

Both groups are making their detailed protocols available to researchers online.

Methods and compositions for DNA fragmentation and tagging by transposases
Multibase delivery for long reads in sequencing by synthesis protocols
Determination of KIR haplotypes associated with disease
Methods and apparatus for detecting molecular interactions using FET arrays
Recombinant polymerases for improved single-molecule sequencing
Methods and apparatus for single-molecule sequencing using energy transfer detection

In Nature this week: factors affecting the success of whole-genome sequencing for routine clinical diagnosis, and more.

A large meta-analysis from an international team reports that nature and nurture have about an equal overall influence on human traits.

The Lasker Foundation's Claire Pomeroy laments the state of NIH funding at Forbes.

Social media is changing how scientists discuss research, as tweets from University of Chicago's Yoav Gilad about a Mouse ENCODE paper have shown, Nature reports.

May
28
Sponsored by
PerkinElmer

This online seminar will demonstrate how RNA-seq analysis in a model organism can provide insights into human disease. 

Jun
23
Sponsored by
PerkinElmer

This webinar will demonstrate how automated liquid handling workstations can reduce bottlenecks in library preparation for next-generation sequencing, enabling scientific advances in genomics research that were not possible five years ago.