Sequencing Technology

Institute for Systems Biology head Leroy Hood presented vignettes from last year's pilot project, laying the groundwork for more widespread wellness-focused work.

The partners will develop panels to stratify patients with obesity and diabetes into surgical and alternate intervention groups in an upcoming clinical trial.

The method, published in Nature Biotechnology this week, could work for other long-read data, such as from Oxford Nanopore's MinIon. 

Canadian researchers have found some 300 loci that appear to predispose American eels to better survive in fresh or brackish water.

The partners will use Cypher's software to diagnose rare diseases in the Clinic's unique patient population, which includes Amish and Mennonite patients.

Methods and compositions for DNA fragmentation and tagging by transposases
Multibase delivery for long reads in sequencing by synthesis protocols
Determination of KIR haplotypes associated with disease
Methods and apparatus for detecting molecular interactions using FET arrays
Recombinant polymerases for improved single-molecule sequencing
Methods and apparatus for single-molecule sequencing using energy transfer detection

The Guardian discusses whether big science projects are worth the loss of resources available for other scientific pursuits.

An NEJM update from the ClinVar team highlights the difficulties of interpreting genetic variants.

In Nature this week: genomic analysis of high-grade serous ovarian cancer, and more.

The new Riken president outlines some of his plans for the institute.

Jun
23
Sponsored by
PerkinElmer

This webinar will demonstrate how automated liquid handling workstations can reduce bottlenecks in library preparation for next-generation sequencing, enabling scientific advances in genomics research that were not possible five years ago.