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NEW YORK (GenomeWeb) — Regulus Therapeutics this week announced that it had priced its previously announced public offering of roughly 5.3 million shares of its common stock at $17 apiece, valuing the transaction at about $90 million.

Title: Construction of Protein-responsive shRNA/RNAi Control System Using RNP Motif
Patent Number: 8,871,437

NEW YORK (GenomeWeb) — Regulus Therapeutics this week released interim results from an ongoing Phase I study of its microRNA-targeting hepatitis C therapy RG-101, which showed that a single subcutaneous dose of the drug could trigger an average 4.1-log reduction in viral loads in patients — a num

This story has been updated to include comments on the validity of the published research.

NEW YORK (GenomeWeb) — Two independent research teams this month published data revealing new roles for two key components of the canonical RNAi pathway — Argonaute-1 and Dicer — in the control of constitutive and alternate splicing, and in transcription termination and the maintenance of genomic

NEW YORK (GenomeWeb) — Alnylam Pharmaceuticals this week announced that it has launched a program called Alnylam Assist to provide free screening to patients with certain genetic diseases, namely the ones for which the company is developing treatments.

NEW YORK (GenomeWeb) — Tekmira Pharmaceuticals this week announced that it has started limited manufacturing of a new version of its siRNA Ebola treatment TKM-Ebola to specifically target the Guinea variant of the disease that is responsible for the current outbreak in Africa.

Title: Methods and Compositions for Increasing RNA Interference
Patent Number: 8,865,668
Filed: Feb. 20, 2009

NEW YORK (GenomeWeb) — Rosetta Genomics said today that it is collaborating with the Institute of Molecular Translational Medicine (IMTM) at Palacky University in the Czech Republic to validate and develop a new thyroid cancer diagnostic tool.

NEW YORK (GenomeWeb) — Biocept and Rosetta Genomics said this week that they will pair Biocept's circulating tumor cell isolation technology with Rosetta's microRNA analysis platforms to investigate the possibility of developing blood-based cancer diagnostics and therapeutic response assays.

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

Two patients fell ill, and one subsequently died, following a fecal microbiome transplant that harbored multi-drug-resistant bacteria, according to the New York Times.

Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

In Science this week: almond reference genome, and more.