RNA-seq Sequencing Study Uncovers MERS-Related Coronavirus in Swiss Bats Researchers used metagenomic DNA and RNA sequencing to identify viruses from dozens of viral families in bat samples collected across Switzerland. Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease Researchers saw convergent subclones crop up in early-stage, estrogen receptor-positive breast cancers that dodged endocrine- and CDK4/6 inhibitor-based therapies. New Algorithms Enable Direct Nanopore-Based Detection of Additional RNA Modifications Premium The method was used to analyze two epigenetic modification types that were previously undetectable with Oxford Nanopore sequencing. Macrophage Subpopulation May Predict Kidney Cancer Recurrence, Serve as Drug Target The macrophage population, which expressed higher levels of three genes, was enriched in tumors of patients who experienced recurrence after surgery. Caris Life Sciences, Fueled by New Funding, Plans to Expand Liquid Biopsy Testing Premium The company expects to launch testing for advanced cancer patients this year, with studies now running to expand to cancer screening and monitoring applications. May 13, 2021 Viome Forays Outside Molecularly Informed DTC Wellness Testing With Oral Cancer Assay Premium May 13, 2021 Blood Cancer Genetic Risk Loci Found in Retriever Dogs May 12, 2021 Early-Stage Lung Cancer Development Traced in Single-Cell RNA Sequencing Study May 10, 2021 Severe COVID-19 Patients Show Antiviral Immunity Defects in Single-Cell Analysis May 7, 2021 Breast Cancer Immunotherapy Response Markers Emerge From Single-Cell Sequencing Study Apr 23, 2021 Startup OncXerna Therapeutics Explores Tumor Microenvironment to Help Guide Cancer Treatment Premium Apr 15, 2021 At ACMG, Mechanism for Common Breast Cancer Locus Proposed From Functional Analysis Apr 15, 2021 Rosalind Partners with Geninus, Helixrus to Bring Single-Cell Software to Asian Markets Apr 13, 2021 Cofactor Genomics Begins Multi-Site Clinical Trial for Immunotherapy Prediction Assay Apr 9, 2021 Gene Expression Score IDs PD-1/PD-L1 Immune Checkpoint Inhibitor Resistance in Bladder Cancers Apr 6, 2021 Uterine Leiomyosarcoma Sequences Point to Potentially Targetable Somatic Mutations Apr 2, 2021 Alzheimer's Disease Genomes Lead to Novel Loci Involved in Synaptic Function Mar 31, 2021 Human Gut Microbiome Continues to Develop Through Early Childhood Mar 26, 2021 Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts Mar 25, 2021 SARS-CoV-2 Study Implicates Saliva in Viral Transmission Mar 24, 2021 Scipher Medicine Raises $82M in Series C Financing Mar 23, 2021 Long-Read Sequencing Emerges as Useful Tool to Study RNA Isoforms Premium Mar 16, 2021 Cofactor Genomics Cements Clinical Diagnostic Plans as Immunotherapy Prediction Data Builds Premium Mar 16, 2021 NeoGenomics, Elevation Oncology Partner on NRG1 Fusion Testing for Clinical Trial Enrollment Mar 11, 2021 Parse Biosciences Lowers Cost Barriers to Single-Cell Transcriptomics Research Premium Load More Breaking News Quest Diagnostics to Offer Biocept's Target Selector NGS Lung Cancer Test Novacyt 2020 Revenues Surge on Strong Demand for SARS-CoV-2 Testing Products Leidos Wins CDC Bioinformatics Contract Worth up to $13M Thermo Fisher Scientific Next-Generation SARS-CoV-2 PCR Test Nabs CE-IVD Mark Cytosine Base Editor Enables Genome-Wide Genetic Function Screening G42 Healthcare, Seegene to Offer Mobile Molecular Diagnostic Labs in Middle East, North Africa The Scan Renewed Gain-of-Function Worries The New York Times writes that the pandemic is renewing concerns about gain-of-function research. Who's Getting the Patents? A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports. Other Uses CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2. PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.