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RNA-seq

Feb 25, 2021

Nature Studies Present Single-Cell Map of Cell Cycle, Approach Identifies Cancer Treatment Resistance Pathways, More

In Nature this week: spatiotemporally resolved map of the human cell cycle, folding single-cell RNA sequencing into cancer drug studies, and more.

Feb 24, 2021

Cell Studies on SARS-CoV-2 Spike Variant, Host Transcriptomes, Glioma-Infiltrating T Cells

In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.

Feb 23, 2021

PNAS Papers on Breast Cancer Immunotherapy, Histone Mutations, Mosquito Mapping

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.

Feb 22, 2021

Multiple Myeloma Therapy Targets, Resistance Pathways Identified With Single-Cell Sequencing

The researchers found new molecular pathways of resistance, including hypoxia tolerance, protein folding, and mitochondria respiration.

Feb 17, 2021

Nucleic Acids Research Papers on Myotonic Dystrophy Splicing, SV Genotyping, Epigenetics Assay

In Nucleic Acids Research this week: targeted splice sequencing study of myotonic dystrophy, structural variant genotyping tool, and more.

Feb 11, 2021

Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes

Genomic, transcriptomic, proteomic, and post-transcriptional modification features in nearly 100 GBM tumors offered clues to tumor biology, revealing four immune subtypes.

Feb 10, 2021

Genome Research Studies on Primate Evolution, Gene Fusions, Expression Prediction

In Genome Research this week: selection on cognition genes in primates, algorithm to find gene fusions, and more.

Feb 08, 2021

Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region

Spatial expression features in six layers of the human dorsolateral prefrontal cortex provided a look at laminar markers and discovered ties to neuropsychiatric disease genes.

Feb 05, 2021

Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State

The researchers said this unexpected homogeneity in the cellular identity of neuroblastoma could lead to the development of targeted treatments.

Feb 05, 2021

Science Papers Examine Role of Autism-Linked Gene in Birds, Genetic Signatures of COVID-19 Outcomes

In Science this week: knocking down an autism-linked gene in young birds influences learning new songs, more.

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The Scan

Even Bigger

Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.

Got Into the Lab Machines

Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.

Not Going to Pay

Science reports that a Dutch research funding agency is combating a ransomware attack.

Science Papers Present Haplotype-Resolved Genomes, MiRNA-Linked Complex Tied to Ribosomal Protein Production

In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.

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