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RNA-seq

In Nature this week: spatiotemporally resolved map of the human cell cycle, folding single-cell RNA sequencing into cancer drug studies, and more.

In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.

The researchers found new molecular pathways of resistance, including hypoxia tolerance, protein folding, and mitochondria respiration.

In Nucleic Acids Research this week: targeted splice sequencing study of myotonic dystrophy, structural variant genotyping tool, and more.

Genomic, transcriptomic, proteomic, and post-transcriptional modification features in nearly 100 GBM tumors offered clues to tumor biology, revealing four immune subtypes.

In Genome Research this week: selection on cognition genes in primates, algorithm to find gene fusions, and more.

Spatial expression features in six layers of the human dorsolateral prefrontal cortex provided a look at laminar markers and discovered ties to neuropsychiatric disease genes.

The researchers said this unexpected homogeneity in the cellular identity of neuroblastoma could lead to the development of targeted treatments.

In Science this week: knocking down an autism-linked gene in young birds influences learning new songs, more.

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Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.

Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.

Science reports that a Dutch research funding agency is combating a ransomware attack.

In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.