RNA-seq

The platform integrates whole exome and RNA sequencing for downstream RNA-based drug repurposing to treat patients with relapsed multiple myeloma.

This Week in Science

In Science this week: single-cell mRNA sequencing of human renal cells, and more.

By sequencing 72,501 individual kidney cells, researchers saw some shared transcriptional patterns in kidney cancers and developing or adult kidneys.

Single-cell RNA sequencing from mouse trachea and human bronchial epithelial cells unearthed new cell types, including ionocytes enriched for CFTR expression.

This Week in Science

In Science this week: gene linked to eusociality in ants, and more.

Veracyte anticipates that it can tap into the growing precision medicine market by leveraging its database of RNA sequencing data for thyroid and lung cancer. 

The firm will use the proceeds for working capital, but said it may also acquire or invest in complementary technologies or businesses.

The researchers found that protocols that use random sequence adapters as opposed to fixed sequence adapters have less bias in small RNA sequencing.

In Genome Biology this week: processing and analyzing single-cell transcriptome data, computational strategy for designing CRISRP single guide RNAs, and more.

Researchers characterized genetic, transcriptomic, and clinical features in advanced prostate cancers that emerged from treatment.

Pages

The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.