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recombination

The ancestor of a bat coronavirus may have obtained a receptor binding motif found among pangolin coronaviruses through a recombination event.

Researchers analyzed data from 23andMe and the UK Biobank to find that errors of recombination, like uniparental disomy, can be present among healthy individuals.

With single-cell genome sequencing, recombination assays, and other approaches in mouse cells, researchers identified factors affecting DNA crossover.

In Science this week: high-resolution map of human genetic recombination, and more.

Decode Genetics researchers used the map to examine how often and where recombination events and de novo mutations occur in the human genome.

In Science this week: recombination hotspots, journal website hijacking, and more.

Based on comparisons between piRNA clusters in mouse, rat, and other mammalian genomes, University of Michigan researchers found evidence that piRNAs are likely under positive selection and capable of rapid expansion.

The University of Maryland, Baltimore is now participating in Horizon's "Targeting Cancer Consortium," in which the company supplies its gene-engineering platform to academic researchers, who create cellular disease models that Horizon in-licenses and sells to drug makers.

An international research team has sequenced the 1.4 million base pair genome of a Wolbachia pipientis strain that infects Drosophila simulans and causes cytoplasmic incompatibility during the fly's mating process.

CalTech's Peter Bossaerts and colleagues studied whether giving participants equal shares of an invention, and the right to trade them, is better than existing patent models. Bossaerts discussed some of the study's implications for current patent-based economies in a BTW interview.

AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

Time magazine looks into how liquid biopsies are changing cancer care.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.