recombinase polymerase amplification Rice University Team Develops POC HPV Test Combining Isothermal Amplification, Lateral Flow Premium The assay detects HPV 16 and HPV 18 DNA within 45 minutes and is intended to be used in low-resource settings. Midge Medical Receives CE Mark for Handheld Isothermal MDx, COVID Test The firm obtained the CE-IVD ahead of the implementation of the In Vitro Diagnostic Regulation, and it expects to launch the system in Germany in the fourth quarter. Harvard-Led Team Develops Handheld Device for DNA, RNA Amplification, Detection Premium The portable device runs an isothermal amplification assay to detect genetic material from strains of tuberculosis in resource limited areas. International Team Begins Field Trials for Solar-Powered 'Suitcase Lab,' Ebola Assay Premium The system uses off-the-shelf laboratory components and currently runs an Ebola assay based on isothermal amplification chemistry from Alere subsidiary TwistDx. PATH Team Completes Prototype Electricity-free Reusable MDx Platform; Eyes Disposable Version Premium The platform — called NINA for non-instrumented nucleic acid amplification — is designed to work with a wide range of isothermal amplification methods. Dec 12, 2013 Estonian Group Validates Point-of-Care Chlamydia Assay Featuring Isothermal RPA Technology Premium Apr 4, 2013 Isothermal Assay from PATH, Hutch, TwistDx Rapidly Detects Multiple HIV-1 Subtypes Premium Feb 28, 2013 GenomeWeb Feature: Tools for Point-of-Care MDx Available, but Challenges Still Loom Premium Feb 28, 2013 Alere Provides Update on Commercialization Timeline for Nucleic Acid-Based Testing Platforms Premium May 17, 2012 Alere Developing Pair of NAT Platforms with Initial Assays Planned for HIV Viral Load, Flu Premium May 3, 2012 Australian OEM Firm Axxin Readying Readers for Partners' Isothermal Amplification MDx Tests Premium Oct 5, 2011 IP Watch: Recent Patents Related to PCR, Nucleic Acid Amplification, and Sample Prep: Oct 5, 2011 Premium Aug 25, 2011 PATH Using TwistDx's Amplification Tech in Minimally Instrumented HIV Test for Infants Premium Breaking News Biora Therapeutics Settles Claims of Misleading Genetic Testing Advertisements Genetic Overlap Between Schizophrenia, Cardiovascular Disease Risk Uncovered by GWAS Analysis Evvy Closes $14M Series A for Vaginal Microbiome Testing, Launches Add-on STI Screen Consanguinity Contributes to Common Disease Risk, Study Suggests Ginkgo Bioworks, Pfizer Ink RNA Drug Discovery Deal Worth up to $331M The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.