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NIH researchers have uncovered a blood-based microRNA signature that may be able to tell which patients with precursor disease may progress to myeloma.

The kit targets several mRNA biomarkers and is the first in a series of salivary diagnostic kits the firm plans to develop for early-stage disease diagnostics.

An epigenome-wide association study suggests a phenotype called mantling is caused by reduced methylation across a newly detected transposon known as Karma.

Researchers from Stanford University have developed a nine-gene panel and a composite risk model to determine prognosis in non-small cell lung cancer.

The company aims to launch the qPCR-based test in sub-Saharan Africa.

The Belgian MDx firm's sights are set on assays for cancer, infectious disease, and sepsis, as well as new iterations of its flagship Idylla platform. 

The latest addition to the firm's qPCR-based Amplidiag line of tests detects H. pylori as well as that pathogen's resistance to clarithromycin.

The multiplexed qPCR test can detect and differentiate four Dengue serotypes in a single reaction tube and is designed for both diagnosis and surveillance.

Results from the study that identified the 11-gene set were published online today in Science Translational Medicine.

The test helps to identify metastatic colorectal cancer patients for whom treatment with Erbitux (cetuximab) or Vectibix (panitumumab) may be effective because their tumors carry no KRAS mutations.


An Associated Press report says China refrained from releasing the SARS-CoV-2 genome for more than a week in January, frustrating the World Health Organization.

The Lancet and the New England Journal of Medicine have issued expressions of concern regarding the data used in two COVID-19 papers, the New York Times reports. 

Researchers have sequenced the genome of the mayfly, garnering insight into how insects evolved wings, Science reports.

In Genome Research this week: gene expression in primate brain regions, inversions and breakpoint inverted repeats in the human genome, and more.