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proximity ligation assay

Unlike the Hi-C chromosome conformation assay, the Pore-C technique reveals information that's lost with short-read sequencing.

The funding supports development of a low-cost platform for detection of antimicrobial resistance elements in complex microbial communities. 

The VGP released its first 15 high-quality reference genome assemblies today, which are part of the project's first phase to sequence 260 vertebrate genomes.

In a talk at the meeting, Riken's Piero Carninci described the RADICL-seq tool he and his colleagues developed.

The firm has used its proximity ligation method to interpret metagenomic sequence data from a human fecal sample, unraveling new and known genomes in the mix. 

Combining PLA and mass cytometry, the method allows simultaneous measurement in the range of 40 to 50 RNAs and proteins in hundreds of thousands of cells.

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In a study, the method was able to detect the interaction of EGFR with an associated signaling protein and predict response to targeted therapies.

A team led by researchers at the University of Freiburg has developed a microfluidic chip for applying proximity ligation assays to cell signaling studies.

While Thermo Fisher Scientific's purchase of Life Technologies announced this week will no doubt have its greatest impact in the genomics and sequencing space, the deal has potential implications for proteomics, as well.

Researchers at the University of Virginia School of Medicine have devised a method based on Olink Bioscience's proximity ligation assay to observe histone modifications at specific gene loci in single cells.

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AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

Time magazine looks into how liquid biopsies are changing cancer care.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.