proximity ligation assay | GenomeWeb

proximity ligation assay

Combining PLA and mass cytometry, the method allows simultaneous measurement in the range of 40 to 50 RNAs and proteins in hundreds of thousands of cells.

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In a study, the method was able to detect the interaction of EGFR with an associated signaling protein and predict response to targeted therapies.

A team led by researchers at the University of Freiburg has developed a microfluidic chip for applying proximity ligation assays to cell signaling studies.

While Thermo Fisher Scientific's purchase of Life Technologies announced this week will no doubt have its greatest impact in the genomics and sequencing space, the deal has potential implications for proteomics, as well.

Researchers at the University of Virginia School of Medicine have devised a method based on Olink Bioscience's proximity ligation assay to observe histone modifications at specific gene loci in single cells.

A team from the University of Gothenburg working with Life Technologies has published a technique combining reverse transcription and proximity ligation to allow quantitative PCR measurements of the DNA, RNA, and proteins from a single cell.

A team led by researchers at the Kimmel Cancer Center at Thomas Jefferson University this week published a study in Cell suggesting that histone-modifying proteins such as histone methyltran

By Adam Bonislawski
With DNA-based affinity agents gaining prominence as tools for protein capture, scientists and biotech firms are exploring biomarker assays that simultaneously report both genetic and proteomic data.

By Adam Bonislawski
Investment firm Nxt2b has signed an agreement to purchase 49 percent of all outstanding shares of Olink Bioscience for an undisclosed amount.

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Startup companies are taking on personalized medicine, CNET reports.

Bruce Booth writes at Life Sci VC that biotech clusters like Boston and San Francisco are getting even more consolidated.

The Verge speaks with Mark and Scott Kelly, who are the subjects of NASA's Twin Study.

In Genome Biology this week: genes linked to Hirschsprung disease, structural variant patterns in autism, and more.