An integrated proteogenomic analysis led to previously unappreciated treatment targets or prognostic markers in craniopharyngioma, high-grade glioma, and other tumor types.
Researchers built a systematic map of protein-drug interactions to investigate the behaviors of cancer cells and the dependencies of treatment responses.
The study compared SARS-CoV-2 to SARS-CoV-1 and MERS to find viral commonalities, and combined the analyses with real-world clinical data to suggest treatments.
Using proteomic, phosphoproteomic, and genomic data, researchers uncovered informative features in primary and metastatic samples from almost 150 CRC cases in China.
The publisher of the Science family of journals will allow some authors to place peer-reviewed versions of their papers into publicly accessible repositories.