prognostic signature
Bladder Cancer Genomes Reveal Treatment Response-Related Mutations in Driver Gene
Researchers linked ERCC2 mutations to broader somatic mutation and treatment response patterns when they analyzed tumor genome sequences from hundreds of bladder cancers.
Tumor Gene Expression Signature Linked to Chemotherapy Response in Colon Cancer Cases
Based on hundreds of stage II and III colon cancer samples, researchers uncovered and validated a 10-gene signature linked to adjuvant chemotherapy response.
Investigators last month published early results, which they believe have set a solid foundation for the independent value of their novel signature.
Hip Fracture Risk Linked to Blood Plasma Protein Score
Researchers developed a hip fracture proteomic risk score that appeared transferable across distinct aptamer-based and double antibody-based proteomic profiling approaches.
Plasma Proteome Study Finds Biomarkers for Severe, Fatal COVID-19
Researchers profiled thousands of plasma samples to untangle protein signatures in patients with increasing COVID-19 severity treated at 15 US hospitals.