prognostic signature
Brain Cancer Study Reveals Immune Cell Populations Linked to Aggressive Subtype
Researchers used single-cell RNA sequencing and spatial transcriptomics to find two myeloid-derived suppressor cell subsets supporting the growth of an aggressive glioblastoma.
TRACERx Lung Cancer Study Validates Prognostic Clonal Gene Expression Test
TRACERx researchers studied the 23-transcript ORACLE clonal expression biomarker, prospectively linking ORACLE risk classification to lung adenocarcinoma survival.
Bladder Cancer Genomes Reveal Treatment Response-Related Mutations in Driver Gene
Researchers linked ERCC2 mutations to broader somatic mutation and treatment response patterns when they analyzed tumor genome sequences from hundreds of bladder cancers.
Tumor Gene Expression Signature Linked to Chemotherapy Response in Colon Cancer Cases
Based on hundreds of stage II and III colon cancer samples, researchers uncovered and validated a 10-gene signature linked to adjuvant chemotherapy response.
Investigators last month published early results, which they believe have set a solid foundation for the independent value of their novel signature.