polygenic risk score

Researchers identified almost 700 major depression-associated variants using genotyping profiles for around 5 million diverse participants with or without major depression.

The study is evaluating the utility of a prostate cancer risk prediction model based on a polygenic score, family history, and a blended genome-exome sequencing approach. 

Using polygenic risk variant profiles from a prior genome-wide association study, researchers found related brain features using brain imaging data for genotyped individuals.