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polygenic risk score

NHS, Genomics PLC to Integrate Polygenic Risk Scores With Traditional Cardiovascular Risk Factors

A newly launched pilot study aims to demonstrate the effectiveness of genetic risk assessment in preventing cardiovascular disease in England.

International Team Debuts New Platform for DIY Genetic Analysis and Interpretation
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Called Personal Access to Genome and Analysis of Natural Traits, or PAGEANT, the platform enables users to analyze and interpret their genomic data at no cost.

Polygenic Scores Have Low Portability Between Genetic Populations, UK Biobank-Based Study Finds

A polygenic score developed in a UK ancestry group had decreased predictiveness when applied to other genetic ancestry groups, including other European groups.

Embryo Selection From Polygenic Risk Scores Enters Market as Clinical Value Remains Unproven
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Companies are entering the human reproduction field with embryo tests claiming to help minimize genetic risk for a host of complex diseases.

GWAS With Higher Genetic Diversity Lead to More Accurate Use of Polygenic Risk Scores

Increasing diversity in large studies results in substantial improvements in fine-mapping functional variants and portability of polygenic prediction.

Dec 3, 2021

SelfDecode Moves Into B2B Services as it Seeks to Diversify, Increase its Reach
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Nov 16, 2021

SelfDecode Closes $8M Financing Round

Oct 27, 2021

Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger
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Sep 24, 2021

At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change

Sep 16, 2021

Polygenic Risk Scores for Breast, Prostate Cancer Adaptable for Cross-Ancestry Use, Study Shows

Aug 6, 2021

Breast Cancer Genetic Risk Modified by Corticosteroid Use

Aug 2, 2021

Feinstein Institutes for Medical Research Wins $2.9M NIH Grant to Study Polygenic Embryo Screening

Jul 28, 2021

Testosterone-Related Genetic Variants Don't Influence Socioeconomic Status, Study Finds

Jul 28, 2021

Polygenic Cancer Risk Score Mitigated by Healthy Lifestyle, Study Suggests

Jul 21, 2021

Avellino Labs Begins Commercial Push for Expanded Ophthalmology Genetic Test Panel
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Jul 15, 2021

Glaucoma Polygenic Risk Score Appears Similarly Informative to Monogenic Risk Assessment

Jun 8, 2021

NIH Earmarks $38M for Consortium Studying Polygenic Risk Scores in Diverse Populations

Jun 7, 2021

University of Sydney Wins A$1.4M Grant, Teams With Allelica on Cardiac Polygenic Risk Scores

Jun 5, 2021

Myriad Genetics Recalibrates Breast Cancer PRS for All Ancestries in Anticipation of Broader Launch
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May 7, 2021

NorthShore, Sema4 Partnership Aims to Demonstrate Utility of Genomics for Personalized Care
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May 6, 2021

Parkinson's Disease Progression Linked to Five Variants in Genome-Wide Survival Study

Mar 19, 2021

Allelica Wants Polygenic Risk Scores to Become Routine in Heart Disease Care
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Mar 17, 2021

Genomics Plc Looks to Grow 'Genomic Prevention' With Polygenic Risk Scores
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Mar 11, 2021

Allelica Raises $1.75M Seed Round, Moves Headquarters to US

Mar 10, 2021

Polygenic Risk Score Reporting Standards Developed

Breaking News
The Scan

For STEM Students to Stay

New policy changes will make it easier for international STEM students to stay in the US after graduation, the Wall Street Journal reports.

To Inform or Not, To Know or Not

The New York Times writes that some genetic biobanks may re-contact donors if they spot something troublesome, but it notes that not all donors want that information.

Rapid Test Studies

Researchers are examining why rapid tests may be less effective at detecting the Omicron variant and how to improve them, NPR says.

PLOS Papers on SARS-CoV-2 Diversity in Delaware, Metastatic Breast Cancer, Adiposity GWAS

In PLOS this week: genomic analysis of SARS-CoV-2 isolates from Delaware, gene expression and protein-protein interaction patterns in metastatic breast cancer, and more.