Large-Scale Genome Sequencing Study Unravels History, Traits of Understudied African Populations
Researchers at UPenn and their colleagues sequenced the genomes of 180 Africans from 12 indigenous populations, identifying more than 32 million novel SNPs.
Germline Mutation Rates Differ Vastly Across Vertebrate Species; Show Sex Bias in Mammals, Birds
A team led by researchers in Denmark and China sequenced the genomes of 151 parent-offspring trios covering 68 species of mammals, fish, birds, and reptiles.
Gut Microbiome Strains Evolved Along With Humans
The finding that strains of gut microbial species can be specific to a population could have implications for microbiome-based therapies.
Sequencing Study Highlights Vaccine-Dodging Streptococcus Pneumoniae Lineage
Researchers turned to whole-genome sequences to characterize S. pneumoniae serotypes that became prominent after the introduction of a pneumococcal conjugate vaccine.
Spatial Copy Number Variant Maps Shed Light on Clonal Cancer Development
Spatially resolved copy number profiles in malignant and benign tissues across organ types led to the detection of ancestral clones at seemingly cancer-free sites.