paired-end sequencing

The investment bank said that PacBio's SMRT sequencing technology has always been attractive compared to traditional NGS shotgun sequencing.

A new study shows that combining size-based and count-based analysis helps determine whether a copy number aberration originates in the mother, fetus, or both.

Exome sequences and copy number patterns suggest lung adenocarcinoma and squamous cell carcinoma are each marked by specific somatic mutations and driver genes.

The high-quality assembly contains clues to carotenoid pigment accumulation and past evolutionary events in the carrot-containing euasterid II clade.

NEW YORK (GenomeWeb) – By tapping pooled, paired-end sequencing data for hundreds of individuals sequenced through the 1000 Genomes Project, a Case Western Reserve University-led team has identified hundreds of relatively common insertion or deletion variants not included in the human reference g

By Andrea Anderson
NEW YORK (GenomeWeb News) – A Singapore-led team has identified a germline polymorphism that appears to account for reduced drug response in some East Asian cancer patients treated with tyrosine kinase inhibitors.

Pages

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.