paired-end sequencing Broad Institute, MIT Researchers Probe Genome Structure With New In Situ DNA Sequencing Method Premium The method, published in Science, pairs in situ sequencing with NGS using barcodes to provide spatial information on DNA sequences inside tissues. New NGS-Based Tissue Analysis Method Offers Spatial Detail on Transcriptome, Proteins Premium Developed by researchers at Yale University, the method, called deterministic barcoding in tissue sequencing, can map thousands of genes at 10 micron resolution. US Court Orders Illumina to Produce Inventors for Deposition in BGI Patent Lawsuit BGI will have a chance to depose up to nine inventors of patents assigned to Illumina as part of a lawsuit over IP related to sequencing-by-synthesis chemistry. Cowen Initiates Coverage of PacBio at Outperform The investment bank said that PacBio's SMRT sequencing technology has always been attractive compared to traditional NGS shotgun sequencing. Size-Based NIPT Approach Helps Clarify Origin of Subchromosomal Abnormalities Premium A new study shows that combining size-based and count-based analysis helps determine whether a copy number aberration originates in the mother, fetus, or both. May 9, 2016 Lung Cancer Subtypes Have Different Recurrent Mutations, Study Finds May 9, 2016 Carrot Genome Sequenced Aug 26, 2014 Team Scours Paired-End Reads with Discordant Mapping to Detect Indels Missed from Human Reference Genome Premium Mar 19, 2012 TKI Cancer Treatment Resistance Linked to Common Germline Variant in East Asian Populations Mar 14, 2012 PCGP Researchers Find Gene Tied To Neuroblastoma Age-at-Diagnosis Feb 29, 2012 Researchers Report Findings from Ancient 'Iceman' Genome Feb 21, 2012 Phylogenetic Features Point to Human Source for Livestock MRSA Strain Dec 19, 2011 Team Detects Mutations Suspected of Boosting Fitness of Drug-Resistant TB Bacteria Dec 6, 2011 BGI, CIAT Leading International Cassava Genomics Project Oct 7, 2011 Sequencing Study Finds Few Rearrangements in Mouse Induced Pluripotent Stem Cells Oct 25, 2010 Team Sequences First Japanese Genome Jun 7, 2010 Team IDs New Gene Fusions in Prostate and Other Cancers Jun 2, 2010 International Team Sequences Seaweed Genome May 12, 2010 Washington University Team Sequences AML Relapse Tumor May 4, 2010 Genome of Rat Model Reveals 60 Deleted Genes that May be Involved in Hypertension Premium Apr 29, 2010 International Team Sequences Genome of Rat Hypertension Model Mar 10, 2010 RNA Sequencing Studies Provide Insights into Gene Expression in African, European Populations Jan 5, 2010 Sanger Institute Detects Chromosomal Rearrangements in Breast Cancers on Illumina Platform Premium Breaking News Lander, Collins Offer Vision for Advanced Research Projects Agency for Health LetsGetChecked Partners With California Department of Public Health for COVID-19 Sequencing BTIG Initiates Coverage of Berkeley Lights With Buy Rating Quest Diagnostics to Offer Biocept's Target Selector NGS Lung Cancer Test Novacyt 2020 Revenues Surge on Strong Demand for SARS-CoV-2 Testing Products Leidos Wins CDC Bioinformatics Contract Worth up to $13M The Scan Could Cost Billions NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars. Not Quite Sent The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post. DTC Regulation Proposals A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports. PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.