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optical mapping

By combining optical mapping with DNA sequencing, University of Wisconsin-Madison researchers examined  structural variation that occurs in multiple myeloma tumors.

A University of Wisconsin at Madison-led team has used single-molecule optical mapping to unearth structural changes in two human tumors, en route to more extensive analyses of cancer samples using a related single-molecule approach currently under development.

NEW YORK (GenomeWeb News) – OpGen today announced the creation of a public health consortium to evaluate its Whole Genome Mapping technology for strain typing microorganisms that cause health outbreaks.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – OpGen has completed an agreement with new and existing investors to provide the firm with up to $17 million in a Series C financing.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Optical mapping technology firm OpGen has raised $3.5 million in bridge financing.

OpGen has raised $2.1 million in a securities offering, the company disclosed in a filing with the US Securities and Exchange Commission last week.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – OpGen has raised $2.1 million, the Gaithersburg, Md., firm confirmed today.

By Julia Karow
OpGen is betting on structural variation detection in humans as an important niche for its optical genome mapping technology as the company scales up from microbial to mammal-size genomes.

OpGen will provide optical maps and sequence-finishing technology, while IGS will contribute clinically characterized microbial samples and sequencing data from microbial genomics studies.

The collaboration is expected to result in a more complete view of microbial genome architecture.

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The US Patent and Trademark Office is opening another interference proceeding in the CRISPR patent fight.

There's increasing genetic evidence that a number of ancient hominins may have contributed to the human gene pool, according to Discover's The Crux blog.

The Japan News writes that Japan needs to seize the opportunity to ensure that a wide number of people benefit from personalized cancer treatments.

In Cell this week: messenger RNA expression and translation, RNA localization atlas, and more.