optical mapping

With its Direct Labeling and Staining (DLS) chemistry, currently available to early-access users, Bionano is pushing forward with more contiguous genome maps.

At PAG, researchers from the Rockefeller University Vertebrate Genome Laboratory outlined sequencing and assembly strategies for phase 1 of the VGP G10K.

After more than two years of development, the British vendor has matched HPC for sequencing alignment accuracy, at far lower power consumption.

The technology could analyze, in one assay, all structural variants known to be diagnostic and prognostic for blood cancers, potentially replacing serial FISH testing.

Increasingly, researchers are combining sequencing, mapping, and scaffolding technologies to generate more contiguous and accurate reference genomes. 

The public-private consortium, led by the National Institute of Standards and Technology, recently released four new reference materials.

This Week in PLOS

In PLOS this week: gene expression differences in plants susceptible to or resistant to Plum pox virus, novel human pegivirus, and more.

By combining optical mapping with DNA sequencing, University of Wisconsin-Madison researchers examined  structural variation that occurs in multiple myeloma tumors.

A University of Wisconsin at Madison-led team has used single-molecule optical mapping to unearth structural changes in two human tumors, en route to more extensive analyses of cancer samples using a related single-molecule approach currently under development.

NEW YORK (GenomeWeb News) – OpGen today announced the creation of a public health consortium to evaluate its Whole Genome Mapping technology for strain typing microorganisms that cause health outbreaks.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.