optical mapping

With its Direct Labeling and Staining (DLS) chemistry, currently available to early-access users, Bionano is pushing forward with more contiguous genome maps.

At PAG, researchers from the Rockefeller University Vertebrate Genome Laboratory outlined sequencing and assembly strategies for phase 1 of the VGP G10K.

After more than two years of development, the British vendor has matched HPC for sequencing alignment accuracy, at far lower power consumption.

The technology could analyze, in one assay, all structural variants known to be diagnostic and prognostic for blood cancers, potentially replacing serial FISH testing.

Increasingly, researchers are combining sequencing, mapping, and scaffolding technologies to generate more contiguous and accurate reference genomes. 

The public-private consortium, led by the National Institute of Standards and Technology, recently released four new reference materials.

This Week in PLOS

In PLOS this week: gene expression differences in plants susceptible to or resistant to Plum pox virus, novel human pegivirus, and more.

By combining optical mapping with DNA sequencing, University of Wisconsin-Madison researchers examined  structural variation that occurs in multiple myeloma tumors.

A University of Wisconsin at Madison-led team has used single-molecule optical mapping to unearth structural changes in two human tumors, en route to more extensive analyses of cancer samples using a related single-molecule approach currently under development.

NEW YORK (GenomeWeb News) – OpGen today announced the creation of a public health consortium to evaluate its Whole Genome Mapping technology for strain typing microorganisms that cause health outbreaks.

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In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.