optical mapping

After more than two years of development, the British vendor has matched HPC for sequencing alignment accuracy, at far lower power consumption.

The technology could analyze, in one assay, all structural variants known to be diagnostic and prognostic for blood cancers, potentially replacing serial FISH testing.

Increasingly, researchers are combining sequencing, mapping, and scaffolding technologies to generate more contiguous and accurate reference genomes. 

The public-private consortium, led by the National Institute of Standards and Technology, recently released four new reference materials.

This Week in PLOS

In PLOS this week: gene expression differences in plants susceptible to or resistant to Plum pox virus, novel human pegivirus, and more.

By combining optical mapping with DNA sequencing, University of Wisconsin-Madison researchers examined  structural variation that occurs in multiple myeloma tumors.

A University of Wisconsin at Madison-led team has used single-molecule optical mapping to unearth structural changes in two human tumors, en route to more extensive analyses of cancer samples using a related single-molecule approach currently under development.

NEW YORK (GenomeWeb News) – OpGen today announced the creation of a public health consortium to evaluate its Whole Genome Mapping technology for strain typing microorganisms that cause health outbreaks.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – OpGen has completed an agreement with new and existing investors to provide the firm with up to $17 million in a Series C financing.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Optical mapping technology firm OpGen has raised $3.5 million in bridge financing.

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The New York Times reports that as China invests in science, it also is dealing with research fraud.

In PLOS this week: transcriptome study of a cold-tolerant plant, deep sequencing of clinical influenza A samples, and more.

The Atlantic writes that retrotransposons like BovB have proliferated in a number of genomes.

Researchers have sequenced the genome of a man who lived in China some 40,000 years ago, according to UPI.