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oligonucleotides

The acquisition of GeneWorks' oligo business widens IDT's reach in the Asia-Pacific region, the company said.

Agilent filed a lawsuit against Twist nearly a year ago, alleging that Twist Cofounder and CEO Emily LeProust had stolen DNA oligonucleotide synthesis technology. 

SMiLE-seq combines antibody arrays, mechanical trapping, and next-generation sequencing readouts to provide a new platform for characterizing DNA-protein interactions.

Scientists led by Eric Kmiec showed that their strategy of point mutation editing with single-stranded DNA oligos and double-strand breaks works with CRISPR/Cas9. 

Single nucleus sequencing analysis of triple-negative breast tumors indicated that copy number changes occur in bursts early in tumor evolution.

In its court filing, the company said Twist Founder and CEO Emily LeProust stole its technology and breached her confidentiality agreements.

The authors have plans to turn the technology into a kit for sequencing panels to be developed by their startup firm, Searna. 

The new 8,000-square-foot building will support oligonucleotide manufacturing for molecular biology applications such as qPCR, next-generation sequencing, and synthetic biology.

The company'sSan Diegomanufacturing site received ISO 14001:2004 certification, making both of its facilities ISO 14001-certified. 

The structured oligonucleotide probe could allow simultaneous PCR amplification and microarray hybridization, and could enable universal microarrays.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.