oligonucleotides | GenomeWeb

oligonucleotides

Scientists led by Eric Kmiec showed that their strategy of point mutation editing with single-stranded DNA oligos and double-strand breaks works with CRISPR/Cas9. 

Single nucleus sequencing analysis of triple-negative breast tumors indicated that copy number changes occur in bursts early in tumor evolution.

In its court filing, the company said Twist Founder and CEO Emily LeProust stole its technology and breached her confidentiality agreements.

The new 8,000-square-foot building will support oligonucleotide manufacturing for molecular biology applications such as qPCR, next-generation sequencing, and synthetic biology.

The company'sSan Diegomanufacturing site received ISO 14001:2004 certification, making both of its facilities ISO 14001-certified. 

Integrated DNA Technologies has released xGen universal blocking oligos, a line of oligonucleotides that prevent cross-hybridization between adapter sequences or hybridization of adapters to capture probes.

NEW YORK (GenomeWeb News) – TriLink BioTechnologies announced today a licensing deal with QuantiBact to offer twisted intercalating nucleic acid, or TINA, modified oligos.

NEW YORK (GenomeWeb News) – Following its first distribution deal for Asia, Link Technologies today announced another deal covering that region, this time with Japanese firm GeneDesign

NEW YORK (GenomeWeb News) – Link Technologies today announced that it has signed on Zirench Technology to be its distributor in China.

Though the RNAi field was shaken in late 2010 and early 2011 by the decisions of two major pharmaceutical players to drop their in-house development of oligonucleotide medicines, industry insiders saw a modest renewal of big pharma's interest in the gene-silencing technology in 2

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In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.