neuroscience Human Brain Circular RNAs Linked to Neuron Type, Neuropsychiatric Conditions Using deep RNA sequencing, researchers identified cell type- and disease-related circRNAs in brain samples from individuals with or without Parkinson’s or Alzheimer’s disease. Single-Cell, Spatial Genomics Studies Unravel Development of Fetal Spinal Cord The findings, based on single-cell and spatial gene expression analysis of fetal spinal cord samples, could aid the development of spinal cord disease models. NYGC Researchers Give Illumina HiSeq Second Life as Multiplex Spatial Biology Platform Premium PySeq turns old sequencers into spatial proteomics instruments and the Cricut craft cutting machine into a piece of precision scientific equipment. Fast-Evolving Human Genome Sequences Found to Have Brain-Related Regulatory Roles An integrated analysis that spanned thousands of human accelerated regions suggested they harbor regulatory elements with roles in human brain development. Single-Cell Transcriptomes Reveal Neuronal Cell Types in Mouse Brain Region With single-cell RNA-seq on thousands of cells from the lateral hypothalamic area of male and female mice, researchers saw dozens of glutamatergic and GABAergic neuron types. Jul 16, 2018 Verge Genomics Scores $32M in Series A Round Dec 7, 2017 New Giro Health Open Initiative Seeks Answers to Neurodegenerative Diseases Sep 22, 2017 Cold Spring Harbor Team to Use $2.7M NIH Grant to Map Long Range Neural Projections Premium Aug 10, 2017 Neuronal Subtypes Revealed Using Single-Cell Methylation Sequencing Aug 25, 2016 Cold Spring Harbor Team Develops Sequencing Method to Map Neuron Transmissions Premium Feb 27, 2009 The Umbrella Institute Premium Feb 24, 2009 DNA Tests Confirm Remains of Russian Royals Killed During Revolution Feb 12, 2009 ABRF Panel Addresses Challenges of Implementing Mass Spectrometry into Core Labs Premium Jan 28, 2009 Making the Most of a Conference Premium Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.