network modeling

The researchers focused on modeling a signaling pathway that they believe could be a viable target for combination therapies that they hope to explore in clinical trials.

The group will offer free access to omic and clinical data from the project and develop software to help clinicians use the models in patient care.

The strategy could be applied more widely to study the development of other organ systems, and will benefit from new single-cell gene expression analysis technology.

The fifth annual Dialogue on Reverse Engineering Assessment and Methods is seeking participants for the annual evaluation of computational systems biology methods.

Biogen Idec worked with Gene Network Sciences to integrate and analyze genome-wide SNP data, expression data, and clinical data from three time points in more than 70 rheumatoid arthritis patients — a process that ultimately identified several targets, including one "that had not been on the radar screen."

At the Network Biology 2.0 conference, speakers underscored the degree to which the understanding of cancer is being empowered by molecular characterization projects and is accompanied by the desire to select the right populations for clinical trials.

New results from the NASA Twins Study indicate that the immune system may rev up when in space, the Washington Post reports.

Kelvin Droegemeier, the new science advisor, spoke at the American Association for the Advancement of Science meeting, Geekwire reports.

In PNAS this week: whole-genome assembly for the white shark, paper-based microfluidic method for detecting the malaria parasite, and more.

The World Health Organization has announced the members of its gene-editing committee, according to NPR.