network modeling
Computer Model for Combination Therapy Prediction in Triple-Negative Breast Cancer Shows Efficacy
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The researchers focused on modeling a signaling pathway that they believe could be a viable target for combination therapies that they hope to explore in clinical trials.
PrECISE Project to Construct Computational Models to Improve Prostate Cancer Treatment, Care
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The group will offer free access to omic and clinical data from the project and develop software to help clinicians use the models in patient care.
Cambridge Team Builds Transcription Regulatory Network Model from Single-cell Expression Data
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The strategy could be applied more widely to study the development of other organ systems, and will benefit from new single-cell gene expression analysis technology.
The fifth annual Dialogue on Reverse Engineering Assessment and Methods is seeking participants for the annual evaluation of computational systems biology methods.
Biogen Idec worked with Gene Network Sciences to integrate and analyze genome-wide SNP data, expression data, and clinical data from three time points in more than 70 rheumatoid arthritis patients — a process that ultimately identified several targets, including one "that had not been on the radar screen."