The system uses synthetic probes that bind to molecules of interest and then pass through solid-state nanopores, enabling detection of the target molecules.
The nanopore ZMW can enable lower starting amounts of DNA for PacBio sequencing, and may eventually enable direct RNA sequencing.
The team showed in a study this week that they could detect BRAF mutations in thyroid cancer, and believe the method could also allow blood-based early cancer detection.
The company is working on both strand- and exonuclease-based nanopore sequencing as well as developing nanopore sensor technology.
The firm will scale up manufacturing of its nanopore sensor, expand its executive team, and push development of its sequencing and genome mapping applications.
UCSF will analyze Two Pore Guys' handheld nanopore device for its ability to detect a KRAS mutation from patient blood and urine samples.
The UCSC spinout plans to launch a handheld nanopore sensor this year and will partner with diagnostic and other companies to develop assays.
Researchers funded in part by Oxford Nanopore recently published a study showing nanopores can detect proteins at the single-molecule level.
The assembly of the agricultural pest Rhizoctonia solani genome was more contiguous and larger than previous short-read assemblies.
During a live webcast, CTO Clive Brown provided an update on the company's development plans and upcoming updates.
Using DNA to sketch crime victims might not be a great idea, the NYTimes says.
Science has its own problem with sexual harassment. What do we do with the research these abusers produce, Wired asks.
Senate Republicans led by Senator Rand Paul (R-KY) are trying to change how the government funds basic research, reports ScienceInsider.
In Science this week: combining genomics and ecology to better understand the effects of natural selection on evolution, and more.