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nanopore

The Telomere-to-Telomere consortium has already generated a gapless assembly of the human X chromosome and aims to complete all chromosomes over the next two years or so.

Early-access users of the Flongle said the small, inexpensive flow cells allow them to develop new methods quickly and to check the quality of clones and libraries.

Syracuse University researchers have developed a nanopore-based technology that could enable detection of proteins in complex biological samples like serum.

The company had £13.8 million ($18.4 million) in revenues and a net loss of £56.6 million in 2017.

The company will use the funding to build a manufacturing facility, expand commercialization efforts, and develop new products.

Clive Brown, the company's chief technology officer, provided an update on the firm's business and talked about new products and planned improvements.

 

The system uses synthetic probes that bind to molecules of interest and then pass through solid-state nanopores, enabling detection of the target molecules.

The nanopore ZMW can enable lower starting amounts of DNA for PacBio sequencing, and may eventually enable direct RNA sequencing.  

The team showed in a study this week that they could detect BRAF mutations in thyroid cancer, and believe the method could also allow blood-based early cancer detection.

The company is working on both strand- and exonuclease-based nanopore sequencing as well as developing nanopore sensor technology.

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Australia will not be regulating gene editing of plants, animals, and human cell lines as long as no new genetic material is incorporated, reports Nature News.

The Washington Post reports that the US Department of Agriculture told its researchers to label peer-reviewed articles as "preliminary" work.

Researchers have sequenced the genomes of both the coast redwood and the giant sequoia, according to the San Francisco Chronicle.

In PNAS this week: study of epigenetic patterns in mammalian eggs, clonal expansion patterns in CD8+ T cells, and more.