mutation detection | GenomeWeb

mutation detection

A Johns Hopkins University team developed a framework to evaluate approaches to predicting cancer driver genes.

The partners will evaluate several quality control assays for genome editing research, eventually creating a protocol for analyzing mutations in genomic DNA.

The method helps break up the genome by chromosome and reduces the complexity of identifying target genes, which is particularly useful for certain plant genomes.

Researchers applied an unbiased transposon mutagenesis sequencing method called SBCapSeq to assess heterogeneity and driver mutations in a mouse model for myeloid leukemia.

A New York University team used its maximum-depth sequencing method for profiling rare mutations in Escherichia coli in an unbiased manner.

Researchers identified a mutational signature that's more common in urothelial tumors with non-silent somatic mutations in the nucleotide excision repair gene ERCC2.

Toma Biosciences will use Seraseq biosynthetic reference material technology to develop and validate its Toma OS-Seq reagent kits. 

Researchers have found that an anti-viral enzyme has generated clusters of mutations that have affected the evolution of hominid genomes.

Researchers have found that mutations present in medulloblastoma tumors at relapse differ substantially from those present at diagnosis.

Researchers shared results from a benchmark study both identifying weaknesses and laying the groundwork for more accurate characterization of somatic mutations.

Pages

In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.