mutation detection Individuals With Polymerase Defects Have Increased Somatic Mutations, But Not Increased Aging The findings suggested to the researchers that the increase in somatic mutations observed as people get older may not be the sole cause of aging-related diseases. Lung Cancers in Non-Smokers Fall Into Informative Molecular Subtypes Whole-genome sequencing of lung cancers in never smokers highlighted three copy number-based subtypes, along with alterations linked to patient outcomes. Genetic Analyses Trace How Mutations Accumulate in Cells of the Human Body Over Time Four new studies have followed somatic mutations that arise in human cells to unravel cell lineages and examine the development of cancer. Science Papers Explore Germline Mutational Processes, Molecular Origins of Barrett's Esophagus In Science this week: a compendium of mutational processes in the human germline, and more. DNA 'Damagenome' May Provide Disease Clues, Study Suggests Investigators used a new approach for detecting spontaneous DNA damage, highlighting high-damage genes and functional pathways with potential disease ties. Apr 16, 2021 OncoDiag Taking Aim at Broader Adoption of Molecular Multiplex Test for Bladder Cancer Recurrence Premium Mar 4, 2021 At AGBT, Two Labs Share SARS-CoV-2 Genomic Surveillance Experience Premium Mar 3, 2021 Agena Rolls out Seq-It SARS-CoV-2 Variant Panel Globally for Use on MassArray System Premium Jan 27, 2021 Small Cell Lung Cancer Study Uncovers Disease-Associated Germline Mutations Jan 13, 2021 Autism Spectrum Disorder Study Finds Contribution From De Novo Tandem Repeat Mutations Jan 11, 2021 Multi-Cancer Molecular Screening Assays Primed for Clinical Implementation in 2021 Premium Jan 7, 2021 Identical Twins Have Non-Identical Genomes, Study Finds Jan 7, 2021 Clear Labs, Integrated DNA Technologies Expand Partnership to Include COVID-19 Testing Dec 9, 2020 Appendiceal Cancer Sequences Suggest Distinct Mutation Patterns in Early-, Late-Onset Cases Nov 25, 2020 Recurrent SARS-CoV-2 Virus Mutations Do Not Increase Transmissibility, Study Finds Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Nov 18, 2020 MSK Study Suggests Germline Tests May Miss Mosaic Cancer Risk Mutations in Some Patients Premium Oct 29, 2020 Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies Oct 27, 2020 Clonal Hematopoiesis Mutation Study Reveals Risk of Treatment-Related Cancer Oct 14, 2020 Developmental Disorder Study Identifies 28 Novel Disease Genes Oct 7, 2020 Post-mortem Melanocyte Mutations Provide Melanoma Clues Oct 1, 2020 Cancer Clues Gleaned from Somatic Mutation Patterns in Normal Bladders Sep 15, 2020 Pancreatic Cancer Treatment Clues Uncovered From Genomic, Chromatin Profiles Jul 21, 2020 Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations Jun 9, 2020 Glioblastoma Genomes Point to Non-Coding Driver Mutations Load More Breaking News Genomic Analysis of China's Bronze Age Tarim Basin Mummies Suggests Local Origins Relationship of Sitting Bull Descendant Verified With Ancient DNA From Lock of Hair Immunai Closes $215M Series B Round DNAe, Imperial College London, U of Leicester to Develop NGS-Based Breast Cancer Monitoring Test Illumina, Israel Ministry of Health to Pilot Genome Sequencing for Diagnosing Critically Ill Infants GenomSys Gains CE Mark for New Genomic Analysis Software The Scan Panel Recommends Pfizer-BioNTech Vaccine for Kids CNN reports that the US Food and Drug Administration advisory panel has voted in favor of authorizing the Pfizer-BioNTech SARS-CoV-2 vaccine for children between 5 and 11 years old. Sharing How to Make It Merck had granted a royalty-free license for its COVID-19 treatment to the Medicines Patent Pool, according to the New York Times. Bring it Back In Bloomberg reports that a genetic analysis has tied a cluster of melioidosis cases in the US to a now-recalled aromatherapy spray. Nucleic Acids Research Papers on SomaMutDB, VThunter, SCovid Databases In Nucleic Acids Research this week: database of somatic mutations in normal tissue, viral receptor-related expression signatures, and more.