mutation detection | GenomeWeb

mutation detection

Using a new mathematical model, researchers uncovered mutational signatures related to homologous recombination deficiency in up to one-fifth of breast cancers.

Woolly mammoths

A mammoth from Wrangel Island that was alive close to the time the species went extinct showed signs of genomic deterioration compared with an older mammoth.

Mutation and predicted neoantigen profiles for more than 63,000 tumors suggests it would be difficult to design a broadly beneficial cancer vaccine.

The Cancer Genome Atlas Research Network team uncovered new mutations and amplifications in their cohort of primary cervical cancers.

A Johns Hopkins University team developed a framework to evaluate approaches to predicting cancer driver genes.

The partners will evaluate several quality control assays for genome editing research, eventually creating a protocol for analyzing mutations in genomic DNA.

The method helps break up the genome by chromosome and reduces the complexity of identifying target genes, which is particularly useful for certain plant genomes.

Researchers applied an unbiased transposon mutagenesis sequencing method called SBCapSeq to assess heterogeneity and driver mutations in a mouse model for myeloid leukemia.

A New York University team used its maximum-depth sequencing method for profiling rare mutations in Escherichia coli in an unbiased manner.

Researchers identified a mutational signature that's more common in urothelial tumors with non-silent somatic mutations in the nucleotide excision repair gene ERCC2.

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Ivanka Trump and Secretary of Education Betsy DeVos call on girls to pursue STEM careers, the Associated Press reports.

Some science companies will be taking part in next month's March for Science, Fortune reports.

In Genome Research this week: longitudinal study of Burkholderia cenocepacia isolates from cystic fibrosis patients, long-read assembly approach, and more.

Shale oil companies are turning to DNA sequencing to find spots to drill, Reuters reports.