multi-gene assays
Ambry Genetics Data Suggests RNA-seq Can Boost Variant Interpretation in Understudied Ethnic Groups
A retrospective analysis suggested that variant classification can be improved in non-white individuals by incorporating paired RNA sequence data.
Exact Sciences Oncotype DX Identifies Postmenopausal Breast Cancer Patients Who Can Forgo Chemo
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The results, presented at SABCS this week, leave open whether the added benefit from chemo seen in premenopausal women may be due to chemo-induced hormone reduction.
Spatial Analysis Startup Resolve Biosciences Launches With $24M Series A Financing Round
The Germany-based company is developing Molecular Cartography, a technology that offers multiplexed analysis of gene expression in tissues.
ESMO Recommendations Outline Use of Next-Gen Sequencing in Metastatic Cancer Patients
The society recommends routine use of multigene NGS for a handful of metastatic cancers, as well as in the context of clinical trials at academic centers.
Gene Panel Finds Pathogenic Variants Missed by Standard Tests in 5 Percent of Familial Cancer Cases
The researchers profiled 44 cancer-related genes in 191 individuals with familial breast cancer, colorectal cancer, or other forms of early-onset cancer.