multi-gene assays Exact Sciences Oncotype DX Identifies Postmenopausal Breast Cancer Patients Who Can Forgo Chemo Premium The results, presented at SABCS this week, leave open whether the added benefit from chemo seen in premenopausal women may be due to chemo-induced hormone reduction. Spatial Analysis Startup Resolve Biosciences Launches With $24M Series A Financing Round The Germany-based company is developing Molecular Cartography, a technology that offers multiplexed analysis of gene expression in tissues. ESMO Recommendations Outline Use of Next-Gen Sequencing in Metastatic Cancer Patients The society recommends routine use of multigene NGS for a handful of metastatic cancers, as well as in the context of clinical trials at academic centers. Gene Panel Finds Pathogenic Variants Missed by Standard Tests in 5 Percent of Familial Cancer Cases The researchers profiled 44 cancer-related genes in 191 individuals with familial breast cancer, colorectal cancer, or other forms of early-onset cancer. NSGC Panel Divided on Whether Newly Diagnosed Breast Cancer Patients Should Undergo Panel Testing Premium Genetic testing results increasingly inform clinical decisions, though the inclusion of hereditary risk genes beyond BRCA1, BRCA2, and PALB2 sparked debate. Oct 3, 2019 Study Finds Breast, Ovarian Cancer Gene Tests Cost-Effective for Unselected Breast Cancer Patients Jun 4, 2019 Color Panel Reveals Hereditary Cancer Risk in Trinidad and Tobago Breast Cancer Patients Premium Dec 6, 2018 Myriad Genetics Describes Advancement of Hispanic-Specific Breast Cancer Polygenic Risk Score Premium Nov 3, 2017 CMS 14-Day Rule Revisions Ease Precision Medicine Access for Patients, Stakeholders Say Premium Apr 21, 2017 Paradigm Hopes Registry Data Will Support Utility for Cancer Testing Beyond DNA Premium Mar 24, 2016 Study Reveals Racial, Socioeconomic Disparity in Genomic Testing in Early Breast Cancer Nov 18, 2015 Final CMS 2016 Lab Fee Schedule Maintains Reimbursement Rates for Several Multi-Analyte Tests Aug 13, 2015 Study Assesses Management Impact of Multigene Panels in Hereditary Breast And Ovarian Cancer Sep 4, 2012 CMS Initial Ruling Places Genetic Tests in Lab Fee Schedule; Favors Gapfill to Fix Payment Aug 28, 2012 Transgenomic Acquires Rights to Scoliosis Prognostic Test Jun 21, 2011 OGT Gets $2.6M Grant to Develop Tumor Profiling Assay May 24, 2011 Nestle Health Science Buying Prometheus Laboratories Mar 8, 2011 XDx's AlloMap Gets Positive Determination from Aetna Feb 25, 2011 Signal Genetics Adds Precision Therapeutics to Suit Feb 14, 2011 Signal Genetics Sues Med BioGene Jul 8, 2009 St. Gallen's Recommendations May Impact Adoption of Leading Breast Cancer Genetic Tests Premium Breaking News Cytosine Base Editor Enables Genome-Wide Genetic Function Screening G42 Healthcare, Seegene to Offer Mobile Molecular Diagnostic Labs in Middle East, North Africa JP Morgan, Cowen Initiate Coverage of Singular Genomics Systems Top Five Articles on GenomeWeb Last Week: Danaher, Becton Dickinson, 23andMe, and More Berry Oncology, Alibaba Health Partner to Offer Early Cancer Screening, Health Services Roche Receives FDA EUA for PCR-Based, Point-of-Care SARS-CoV-2 Test The Scan Renewed Gain-of-Function Worries The New York Times writes that the pandemic is renewing concerns about gain-of-function research. Who's Getting the Patents? A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports. Other Uses CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2. PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.