modeling
Preterm Birth Biology Unraveled With Multiomics, Machine Learning
A multiomic analysis in low- and middle-income countries pointed to some of the genes and processes contributing to known epidemiological risk factors for preterm birth.
Human Evolution Study Suggests Multiple Early Lineages in Africa
Tapping into genetic diversity in present-day African populations, researchers saw signs of "weakly structured" early human lineages marked by mixing and muted genetic differentiation.
Extrachromosomal DNA Appears to Boost Cancer Adaptability, Impact Drug Response
Researchers demonstrated that random inheritance of extrachromosomal DNAs can boost cancer development, while helping a subset of tumor cells adapt to evade treatment.
SARS-CoV-2 Genome Analysis Reveals Fitness-Enhancing Mutations
Using a new modeling approach, investigators analyzed sequences for nearly 6.4 million SARS-CoV-2 isolates, uncovering fitness-related mutations and clues to the virus's evolution.
Demographic Modeling of Ancient Genomes Indicates First Farmers Arose From Mixing of Populations
The results suggest early farmers were a mix of a Southwest Asian population and a western hunter-gatherer population that went through a strong bottleneck.