modeling | GenomeWeb

modeling

VISION aims to provide validated regulatory modules, quantitative models for gene regulation, and guides for translating research from mouse models to human.

The researchers' findings could have wide-ranging implications for how the modeling tool should be used and how reliable the data from it is in biodiversity and evolution studies.

Analysis of a gene associated with basal progenitor cell expansions in the brain suggests a single splice site change led to human-specific forms of the gene transcript.

The model could shift which patients receive gene expression profiling assays but might not change the number of tests ordered.

Jax researchers will aim to study why some individuals are more likely to start using drugs, or to get addicted to them.

The study found that combining whole-genome expression or genome-wide methylation data with clinical data improves survival predictions in breast cancer cases.

Early results of a study suggest at least some recurrent gene mutations differ by breed for dogs affected by B-cell and/or T-cell lymphomas.

african killifish

The African turquoise killifish, which lives only four to six months, has been transformed into a platform for genetic research with the help of CRISPR/Cas9 genome editing.

A computational model developed by researchers at Johns Hopkins and Harvard Universities has provided a possible explanation for why HIV treatment regimens that include protease inhibitors fail even though there are no observed resistance mutations in the viral genome.

The algorithm, which was developed by researchers at MIT and validated by a team at Novartis, lets users identify regions on antibodies that are prone to aggregation and then predict mutations to improve the stability of biotherapeutic formulations.

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An opinion piece appearing in Newsday likens familial DNA search to stop-and-frisk policies.

The San people of Africa have drawn up a code of conduct for researchers, according to the Conversation.

In Nature this week: genotypes linked to hip osteoarthritis, and more.

Startup companies are taking on personalized medicine, CNET reports.