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NEW YORK (GenomeWeb) – As part of their effort to develop an RNAi-based therapy for hepatitis B infection, researchers from the University of the Witwatersrand in South Africa have developed self-inactivated lentiviral vectors that generate liver-specific microRNA-based RNAi activators that targe

Title: Methods and Means for Producing Efficient Silencing Construct Using Recombinatorial Cloning
Patent Number: 8,877,435

NEW YORK (GenomeWeb) – Rosetta Genomics today announced a deal to sell tests from Admera Health to oncologists and pathologists.

NEW YORK (GenomeWeb) — A team of scientists from the Scripps Research Institute this week reported the crystal structure of a microRNA bound to human Argonaute 2 both before and after their engagement with a target mRNA, showing how the protein starts off by exposing only a small portion of its g

NEW YORK (GenomeWeb) — A team led by MD Anderson Cancer Center researchers this month published new data demonstrating that breast cancer-derived exosomes are capable of cell-independent microRNA biogenesis and are able to promote tumorigenesis in a Dicer-dependent manner.

NEW YORK (GenomeWeb) — Regulus Therapeutics this week announced that it had priced its previously announced public offering of roughly 5.3 million shares of its common stock at $17 apiece, valuing the transaction at about $90 million.

Title: Construction of Protein-responsive shRNA/RNAi Control System Using RNP Motif
Patent Number: 8,871,437

NEW YORK (GenomeWeb) – Cantor Fitzgerald today initiated coverage of miRNA-based diagnostics firm Rosetta Genomics with a Hold rating and a $4 price target on the company's stock.

NEW YORK (GenomeWeb) — Regulus Therapeutics this week released interim results from an ongoing Phase I study of its microRNA-targeting hepatitis C therapy RG-101, which showed that a single subcutaneous dose of the drug could trigger an average 4.1-log reduction in viral loads in patients — a num

This story has been updated to include comments on the validity of the published research.

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A new analysis suggests warming, not the arrival of humans, led to the extinction of the woolly rhinoceros thousands of years ago, the Economist reports.

Chinese health officials uncovered SARS-CoV-2 viral RNA on imported frozen food, but the New York Times reports catching COVID-19 that way would be unlikely.

The UK has ordered 60 million coronavirus vaccine doses from Novavax and 30 million doses from Janssen, according to the Guardian.

In Science this week: machine learning model predicts whether ion channel mutations will cause disease, and more.