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miRNA

Warnex will market the tests and send tissue samples from its customers to Rosetta's Philadelphia-based lab for analysis.

The application, No. 20060058266, is entitled "Chemically modified oligonucleotides," and claims "composition and methods for making and using chemically modified oligonucleotide agents for inhibiting gene expression," according to its abstract.

Marketing director Dalsoo Kim said the company now sells a PANArray miRNA expression-profiling kit for surveying stem cell-related miRNAs. The launch follows its debut in June of a kit for profiling cancer-related miRNAs.

Warnex Medical Laboratories and Rosetta Genomics have reached an exclusive distribution agreement that applies to three miRview tests in Canada.

Papers of Note: Aug 6, 2009

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RNAi-Related Papers Published July 2009

In the advance online version of Nucleic Acids Research, Santaris investigators reported data identifying miR-155, an miRNA involved in immune-system regulation, as a possible therapeutic target for chronic inflammatory diseases such as rheumatoid arthritis.

Papers of Note: Jul 9, 2009

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RNAi-Related Papers Published June 2009

Using a technique called HITS-CLIP, researchers from Rockefeller University have created a map of microRNA-messenger RNA interactions in the mouse brain.

The release of the data comes on the heels of a publication in Cell showing that therapeutic miRNA delivery could suppress tumorigenesis in a mouse model of liver cancer, which Mirna's CEO said bolsters the company's strategy.

The method, which is detailed in the current issue of Genome Biology, involves using the mean expression value of all expressed miRNAs in a given sample.

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The US National Institutes of Health's All of Us project awarded $4.6 million to the company Color to develop a genetic counseling resource for the program.

The Times of India reports on a pilot study that used genomic testing to determine whether patients had drug-resistant tuberculosis.

New guidelines say that more women may benefit from genetic testing for hereditary breast or ovarian cancer, according to the Los Angeles Times.

In Cell this week: small proteins identified among human microbiome, role for tumor microbes in pancreatic cancer survival, and more.