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MiR-371-3p diminished tolerance to targeted cancer treatment in cell lines and mice, while tolerant cells had enhanced levels of genes regulated by miR-371-3p.
A team of German researchers identified the four-microRNA signature and said it might inform treatment decisions.
Through the acquisition, Miroculus will be able to automate and simplify the detection of miRNAs from blood using Kapplex's digital microfluidic technology.
Genomic, transcriptomic, and methylomic data for more than 150 oligodendroglial tumors uncovered three subgroups within a previously defined low-grade glioma subtype.
The technology uses DNAzyme-based sensors, fluorescent biomarkers, and a high-throughput particle counter to rapid identify rare targets in complex raw samples.
Qiagen has submitted an offer to buy all of Exiqon's shares for DKK18 each, for a total aggregate purchase price of DKK683 million ($103.5 million).
In Nucleic Acids Research this week: atlas of microRNAs from various tissues types, ribosomal RNA gene flanking region sequencing, and more.
A new study by an international team of researchers has found that the microRNA miR-9-5p has a role in the development of schizophrenia.
The company sees microRNAs as the ideal blood-based biomarker for diagnosing and monitoring a number of diseases at the point of care and in the developing world.
In PNAS this week: single-stranded cytosine deamination in E. coli, characterization of herpes simplex virus-1 microRNAs, and more.
Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.
An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.
Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.
In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.