California researchers screened some 850 miRNAs to uncover one that inhibits growth in cancer cells with KRAS mutations, which are linked to poor survival.
MiR-371-3p diminished tolerance to targeted cancer treatment in cell lines and mice, while tolerant cells had enhanced levels of genes regulated by miR-371-3p.
Sistemic will provide its SistemRNA suite of drug development tools in order to accelerate Redx's preclinical development pipeline of more than 250 new drug candidates.
Jay Shendure and his colleagues have developed a new method to more comprehensively identify human cell types, the NY Times reports.
Researchers in the UK and Japan have shown that infertility in mice with three sex chromosomes can be overcome, according to the Guardian.
China is embracing preimplantation genetic diagnosis, Nature News reports.
In PLOS this week: host genetic factors associated with cervical neoplasia progression, population patterns for an ancient flowering rainforest plant, and more.