California researchers screened some 850 miRNAs to uncover one that inhibits growth in cancer cells with KRAS mutations, which are linked to poor survival.
MiR-371-3p diminished tolerance to targeted cancer treatment in cell lines and mice, while tolerant cells had enhanced levels of genes regulated by miR-371-3p.
Sistemic will provide its SistemRNA suite of drug development tools in order to accelerate Redx's preclinical development pipeline of more than 250 new drug candidates.
Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.
The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.
Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.
In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.