miRNA analysis

Molecular analysis of metastatic CRC in the liver has identified three molecular subtypes that can be coupled with clinical risk scores to inform patient risk.

Given the high yield of miRNA markers they were able to isolate, the researchers believe the approach could be commercialized for routine cancer testing.

This Week in PLOS

In PLOS this week: genomic analysis of honeybee disease, microRNA profiles of people with lupus nephritis, and more.

Researchers have developed a spit-based miRNA test to gauge concussion duration in children, NPR reports.

This Week in PLOS

In PLOS this week: genetic networks involved in antibiotic sensitivity, syphilis pathogen proteome, and more.

Researchers from Northwestern University uncovered five circulating microRNAs that differentiate patients with very high- and low-risk prostate cancer.

This Week in PLOS

In PLOS this week: variants that affect COPD biomarkers, high genetic diversity of Cryptococcus gattii in Brazil, and more.

Genomic, transcriptomic, and methylomic data for more than 150 oligodendroglial tumors uncovered three subgroups within a previously defined low-grade glioma subtype.

The researchers used the tool to look at the role of miRNAs in viral infection, but believe it has potential for studying miRNA in many other contexts.

Members of TCGA characterized papillary renal cell carcinomas, uncovering two main tumor groups and several more prognostically informative subtypes.

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Parabon NanoLabs is partnering with law enforcement to use genetic genealogy approaches to solve cold cases, Buzzfeed News reports.

A Columbia University-led team used emergency contact information from medical records to create family trees and estimate disease heritability.

In Science this week: ancient Southeast Asian genomes provide insight on human migration, and more.

NPR says a new report recommends that former research chimpanzees should be moved to retirement sanctuaries unless that move would shorten their lives.