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microbial sequencing

By analyzing metagenomic sequences found in thousands of human mouth and gut samples, researchers tracked down almost 45.7 million distinct microbial genes.

Researchers identified tumor microbe and immune differences in tumor samples from pancreatic ductal adenocarcinoma patients with exceptionally long survival.

In Nature this week: new CRISPR nuclease described, gut bacteria reference, and more.

Two research groups have cultured and sequenced microbes in fecal samples from healthy volunteers, producing new reference genomes for hundreds of species.

In PLOS this week: splice variant linked to lethal condition in bull terriers, sequencing to search for pathogens at hot springs, and more.

The researchers also found that niche-based processes underlie how the skin microbiomes of people living in megacities are assembled.

In PLOS this week: microRNA helps M. tuberculosis escape the immune system, application of genome-scale metabolic models to drug design, and more.

In PNAS this week: multi-omic analysis of Atlantic Ocean samples, miR-351 linked to hepatic fibrosis during Schistosoma infection, and more.

Researchers compared microbes found by swabbing the International Space Station to swabs taken from houses and to the human microbiome.

Higher levels of oral bacteria like Tannerella forsythia and Porphyromonas gingivalis increased the risk of esophageal cancer, though other bacteria had protective effects.

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The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.