Logo

methylome sequencing

Cell-Free DNA Methylome Signatures Show Potential for Early Cancer Detection
Premium

In a study presented at the ASHG annual meeting this week, researchers identified plasma cfDNA methylation profiles that were predictive of certain cancers.

Cell-Free DNA Methylome Sequencing Method Promises Early Cancer Detection, Tissue of Origin
Premium

A newly published method developed by a UCLA-led team shows promise for early cancer detection using cell-free DNA methylation markers.

Children's Mercy Test Drives Addition of Methylation Calls on Pacific Biosciences' Long-Read WGS
Premium

Pacific Biosciences' HiFi sequencing protocol now includes 5mC methylation calls for every genome. What will researchers discover with it?

Canadian Liquid Biopsy Startup Adela to Pursue Cancer Early Detection Tests
Premium

The company raised $60 million last week and will use the funding to develop and validate its DNA methylation-based tests and classifier algorithm.

Liquid Biopsy Startup Adela Launches With $60M Series A Financing Round

The Toronto-based company will use the funding to commercialize its cell-free DNA methylation sequencing technology as an early cancer detection test.

Apr 20, 2021

Nanopore Sequencing Firm Armonica Technologies Progresses Towards Single-Base Detection
Premium

Nov 2, 2020

Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications
Premium

Oct 16, 2020

Pancreatic Cancer Subtype With Poor Outcomes Shows Low Methylation, High Interferon Signature

Sep 21, 2020

Grail Deal Will Enable Illumina to Expand From Tech Innovator to Diagnostics Provider
Premium

Jul 31, 2020

Data Supports Singlera's PanSeer Test as Company Narrows Focus to Colorectal Cancer Detection
Premium

Jul 2, 2020

Translation of Dog Years Into Human Years Updated With Epigenetic Analysis

Aug 28, 2019

Alzheimer's Disease Analysis Leads to Potential Epigenetic Signatures

Aug 7, 2019

UCSD Researchers Develop Assay Combining Methylation Status, Chromosome Conformation Analysis
Premium

Nov 14, 2018

Methylation-Based Cancer Early Detection Method Shows Promise in Preliminary Studies

Nov 5, 2018

Personal Methylome, Transcriptome Profiling Over Time Reveals Illness-Linked Changes

Oct 23, 2018

Decode Researchers Generate Map of Imprinting Patterns in Human Genome

Apr 10, 2018

OHSU Team Develops Combinatorial Indexing Approach for Single-Cell Methylation Sequencing
Premium

Dec 18, 2017

Single-Cell Methylome Sequencing Uncovers Dynamics of DNA Methylation in Human Embryos

Aug 10, 2017

Neuronal Subtypes Revealed Using Single-Cell Methylation Sequencing

Jun 8, 2017

Norwegian Team Plans to Debut Digital PCR-Based Urinary Bladder Cancer Test by Year End
Premium

Mar 15, 2016

Researchers Use Methylation Patterns to Trace Cell-Free DNA Back to Tissue of Origin

Jan 29, 2016

Normal Tissue Adjacent to Breast Tumors Also Exhibits Epigenetic Changes

Dec 10, 2015

Epigenomic Map of Wheat Shows Conservation, Variation of Methylation Among Subgenomes

Jun 5, 2015

McGill Team Develops Epigenetic Panel for Population-Scale Disease Studies
Premium

Jun 1, 2015

Human Methylome Map Reveals Variations by Tissue, Non-Canonical Methylation

Breaking News
The Scan

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.

Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights

Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival.

CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood

A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system.

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.