methylome sequencing Cell-Free DNA Methylome Signatures Show Potential for Early Cancer Detection Premium In a study presented at the ASHG annual meeting this week, researchers identified plasma cfDNA methylation profiles that were predictive of certain cancers. Cell-Free DNA Methylome Sequencing Method Promises Early Cancer Detection, Tissue of Origin Premium A newly published method developed by a UCLA-led team shows promise for early cancer detection using cell-free DNA methylation markers. Children's Mercy Test Drives Addition of Methylation Calls on Pacific Biosciences' Long-Read WGS Premium Pacific Biosciences' HiFi sequencing protocol now includes 5mC methylation calls for every genome. What will researchers discover with it? Canadian Liquid Biopsy Startup Adela to Pursue Cancer Early Detection Tests Premium The company raised $60 million last week and will use the funding to develop and validate its DNA methylation-based tests and classifier algorithm. Liquid Biopsy Startup Adela Launches With $60M Series A Financing Round The Toronto-based company will use the funding to commercialize its cell-free DNA methylation sequencing technology as an early cancer detection test. Apr 20, 2021 Nanopore Sequencing Firm Armonica Technologies Progresses Towards Single-Base Detection Premium Nov 2, 2020 Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications Premium Oct 16, 2020 Pancreatic Cancer Subtype With Poor Outcomes Shows Low Methylation, High Interferon Signature Sep 21, 2020 Grail Deal Will Enable Illumina to Expand From Tech Innovator to Diagnostics Provider Premium Jul 31, 2020 Data Supports Singlera's PanSeer Test as Company Narrows Focus to Colorectal Cancer Detection Premium Jul 2, 2020 Translation of Dog Years Into Human Years Updated With Epigenetic Analysis Aug 28, 2019 Alzheimer's Disease Analysis Leads to Potential Epigenetic Signatures Aug 7, 2019 UCSD Researchers Develop Assay Combining Methylation Status, Chromosome Conformation Analysis Premium Nov 14, 2018 Methylation-Based Cancer Early Detection Method Shows Promise in Preliminary Studies Nov 5, 2018 Personal Methylome, Transcriptome Profiling Over Time Reveals Illness-Linked Changes Oct 23, 2018 Decode Researchers Generate Map of Imprinting Patterns in Human Genome Apr 10, 2018 OHSU Team Develops Combinatorial Indexing Approach for Single-Cell Methylation Sequencing Premium Dec 18, 2017 Single-Cell Methylome Sequencing Uncovers Dynamics of DNA Methylation in Human Embryos Aug 10, 2017 Neuronal Subtypes Revealed Using Single-Cell Methylation Sequencing Jun 8, 2017 Norwegian Team Plans to Debut Digital PCR-Based Urinary Bladder Cancer Test by Year End Premium Mar 15, 2016 Researchers Use Methylation Patterns to Trace Cell-Free DNA Back to Tissue of Origin Jan 29, 2016 Normal Tissue Adjacent to Breast Tumors Also Exhibits Epigenetic Changes Dec 10, 2015 Epigenomic Map of Wheat Shows Conservation, Variation of Methylation Among Subgenomes Jun 5, 2015 McGill Team Develops Epigenetic Panel for Population-Scale Disease Studies Premium Jun 1, 2015 Human Methylome Map Reveals Variations by Tissue, Non-Canonical Methylation Load More Breaking News Imaging Mass Cytometry Discovers Tumor Microenvironment Features Predicting Lung Cancer Outcomes Metastatic Tumor Subtypes Found With Expression Profiling GenomeWeb Top 40 up 4 Percent in January, Following Broader Upswing LumiraDx Receives Notice From Nasdaq Over Missed Listing Requirement Sherlock Biosciences to Acquire Sense Biodetection The Scan Study Links Evolution of Longevity, Social Organization in Mammals With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals. Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival. CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system. Drug Response Variants May Be Distinct in Somatic, Germline Samples Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.