Investigators identified dozens of neuronal subtypes in mouse and human brain samples using single-cell methylation sequencing, including a new neuronal subtype.
The team said their approach may have several applications, including evaluation of cellular response to therapies, and early diagnosis of diseases like cancer.
The researchers published a proof of principle in Nature Communications of a panel designed to look at epigenetic variation in adipose tissue and are using it to study obesity and metabolic syndromes.
NEW YORK (GenomeWeb) – Using epigenetic regulation, the black truffle genome is able to control the transposable elements that make up a large portion of its DNA, an international team of investigators reported in Genome Biology.
Researchers from University College London, have shown that a targeted bisulfite sequencing method using RainDance Technologies' microdroplet PCR system can accurately measure DNA methylation levels at sample sizes as low as 100 nanograms.
An Australian team searches for genetic alterations linked to depression in hopes of developing personalized treatments, the Sydney Morning Herald reports.
