methylation-specific PCR

The contract includes a milestone of approval by the Chinese Food and Drug Agency within the next three years.

The company plans to launch the new qNIPT test, which uses methylation-specific quantitative PCR to detect fetal epigenetic biomarkers, in the near future.

NEW YORK (GenomeWeb) — Iowa City-based Behavioral Diagnostics recently won a one-year, $200,000 Small Business Innovation Research grant from the National Institute on Drug Abuse to fund development of its quantitative measure of cigarette smoking and cessation.

NEW YORK (GenomeWeb) — Biochemists at the University of Konstanz in Germany have created a mutant polymerase with high activity and high mismatch extension selectivity. The new enzyme is a variant of the large Klenow fragment of Thermus aquaticus DNA polymerase, or KlenTaq.

Researchers affiliated with the laboratory of Mike Makrigiorgos at Dana Farber Cancer Institute and Harvard Medical School have demonstrated how their COLD-PCR method can be applied to epigenetics, allowing the enrichment and sequencing of rare unmethylated DNA regions in a background of highly m

A study published this week has shown methylation status in a panel of genes may be useful to non-invasively monitor breast cancer recurrence and treatment response.

With numerous kits on the market for PCR of methylated DNA, researchers may wonder which is the best for bisulfite conversion of various types of real-world samples.

NEW YORK (GenomeWeb News) — Roche said today that it has licensed its emulsion PCR patent portfolio to Sysmex Inostics.

Arizona State University researchers recently published the details of an emulsion-based droplet qPCR platform believed to be the first ever to enable real-time analysis on a continuous-flow system.

NEW YORK (GenomeWeb News) – Molecular diagnostics firm Inostics announced today that its clinical laboratory in Baltimore, Md., has received CLIA licensure, allowing it to offer its non-invasive OncoBeam tumor mutation test.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.