methylation-specific PCR | GenomeWeb

methylation-specific PCR

NEW YORK (GenomeWeb) — Iowa City-based Behavioral Diagnostics recently won a one-year, $200,000 Small Business Innovation Research grant from the National Institute on Drug Abuse to fund development of its quantitative measure of cigarette smoking and cessation.

NEW YORK (GenomeWeb) — Biochemists at the University of Konstanz in Germany have created a mutant polymerase with high activity and high mismatch extension selectivity. The new enzyme is a variant of the large Klenow fragment of Thermus aquaticus DNA polymerase, or KlenTaq.

Researchers affiliated with the laboratory of Mike Makrigiorgos at Dana Farber Cancer Institute and Harvard Medical School have demonstrated how their COLD-PCR method can be applied to epigenetics, allowing the enrichment and sequencing of rare unmethylated DNA regions in a background of highly m

A study published this week has shown methylation status in a panel of genes may be useful to non-invasively monitor breast cancer recurrence and treatment response.

With numerous kits on the market for PCR of methylated DNA, researchers may wonder which is the best for bisulfite conversion of various types of real-world samples.

NEW YORK (GenomeWeb News) — Roche said today that it has licensed its emulsion PCR patent portfolio to Sysmex Inostics.

Arizona State University researchers recently published the details of an emulsion-based droplet qPCR platform believed to be the first ever to enable real-time analysis on a continuous-flow system.

NEW YORK (GenomeWeb News) – Molecular diagnostics firm Inostics announced today that its clinical laboratory in Baltimore, Md., has received CLIA licensure, allowing it to offer its non-invasive OncoBeam tumor mutation test.

Scientists from Arizona State University's Biodesign Institute are using a two-year, approximately $420,000 grant from the National Institutes of Health to further develop a tool that combines laser-based excision and ablation with emulsion-based droplet PCR to profile mRNA expre

A new partnership between diagnostics manufacturer MDxHealth and Ghent University's laboratory of pharmaceutical biotechnology aims to develop epigenomics-based diagnostics for more personalized treatment of cancers and inflammatory diseases.


Harvard's George Church discusses HGP-write with the Journal of the American Medical Association.

In Nature this week: genetic history of HIV in the US, and more.

There are a few projects aimed at addressing the lack of diversity in genomic research, Technology Review reports.

A national assessment shows that US students lag in the sciences, but suggests that achievement gaps are narrowing.