methylation-specific PCR

The JHU technology leverages an epigenetic biomarker panel and a sponge-on-a-string collection device, as well as a PCR-based method, to detect Barrett's esophagus.

The firm believes that data from a recently published study illustrates the advantages of its technology for methylation-specific PCR assays.

The qPCR assay measures methylation of six genes and could help doctors identify aggressive vs indolent prostate cancer more accurately than PSA.

The contract includes a milestone of approval by the Chinese Food and Drug Agency within the next three years.

The company plans to launch the new qNIPT test, which uses methylation-specific quantitative PCR to detect fetal epigenetic biomarkers, in the near future.

NEW YORK (GenomeWeb) — Iowa City-based Behavioral Diagnostics recently won a one-year, $200,000 Small Business Innovation Research grant from the National Institute on Drug Abuse to fund development of its quantitative measure of cigarette smoking and cessation.

NEW YORK (GenomeWeb) — Biochemists at the University of Konstanz in Germany have created a mutant polymerase with high activity and high mismatch extension selectivity. The new enzyme is a variant of the large Klenow fragment of Thermus aquaticus DNA polymerase, or KlenTaq.

Researchers affiliated with the laboratory of Mike Makrigiorgos at Dana Farber Cancer Institute and Harvard Medical School have demonstrated how their COLD-PCR method can be applied to epigenetics, allowing the enrichment and sequencing of rare unmethylated DNA regions in a background of highly m

A study published this week has shown methylation status in a panel of genes may be useful to non-invasively monitor breast cancer recurrence and treatment response.

With numerous kits on the market for PCR of methylated DNA, researchers may wonder which is the best for bisulfite conversion of various types of real-world samples.

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A University of California, Los Angeles-led team has found turning off the CCR5 gene could improve recovery after a stroke, according to Scientific American.

South Dakota lawmakers are to weigh a bill aimed at teaching the strengths and weaknesses of scientific concepts, the Associated Press and KEVN-Black Hills Fox report.

In Science this week: the synthetic genetic system hachimoji, and more.

Thermo Fisher Scientific says it will no longer sell machines in China's Xinjiang region, according to the Wall Street Journal.