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methylation analysis

An epigenetic analysis showed that the tumors all shared a certain DNA methylation signature, but that methylation patterns varied between samples.

In PNAS this week: transcriptional control enables malaria parasite to get around disease control efforts, DNA methylation patterns in the Norway spruce, and more.

Dartmouth researchers characterized 5-methylcytosine and 5-hydroxymethylcytosine marks in more than two dozen glioblastoma samples.

The company has also expanded its current Veracity NIPT to sex chromosomal aneuplodies and twin pregnancies, and plans to offer microdeletion testing next year.

In PLOS this week: methylation in human gametes, microRNAs linked to kidney damage in lupus patients, and more.

By analyzing mutations in tumors from a broad swath of tobacco smoke-related cancer types, investigators identified more than two-dozen mutational signatures.

The DNA methylation age concept, developed by UCLA geneticist Steve Horvath, uses 353 markers obtained from Illumina methylation arrays.

In PLOS this week: germline variants in prostate cancer risk genes, genome of a Zika virus from patient without neurological complications, and more.

London Health Sciences Center researchers published a study validating the accuracy of the method as a potential screening test for symptomatic male patients.

Through their combined genetic and epigenetic study of schizophrenia, the researchers have generated a list of genes affected by risk factors for the disease.

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At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.

Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.

In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.