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methylation analysis

In Genome Research this week, mismatch repair deficiency in C. elegans, retracing transcriptions start site evolution in the human genome, and more. 

The team found that colorectal cancer cells experience substantial increases in somatic mutations compared to normal colorectal cells.

With integrated data for thousands of TCGA tumors, teams explored cancer subtypes, searched for prognostic insights, began mapping immune cell interactions, and more.

The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles.

The researchers used DNA methylation profiles to define 82 central nervous system tumor classes, some of which differed from WHO tumor classes.

The Epigenetics For Female Personalised Cancer Care (EpiFemCare) project recently published its findings in two papers in the journal Genome Medicine.

In Genome Biology this week: peopling of the Sahara, epigenetic reprogramming analysis of liverwort, and more.

A Dutch famine during World War II led to life-long epigenetic changes in individuals whose mothers were pregnant with them at the time.

Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.

A genomic analysis of ependymomas from 42 patients led to nearly 1,700 suspected super enhancers, highlighting potentially targetable genes.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.