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methylation analysis

Many molecularly distinct subgroups emerged from a meta-analysis bringing together more than 1,000 high-grade glioma or diffuse intrinsic pontine glioma cases.

In Genome Biology this week: heritable DNA methylation in Arabidopsis, genetic networks linked to agronomical traits in soybean, and more.

Using data for 34 individuals, researchers tallied human DNA methylation variation across Yakut, Cambodian, Pathan, Mozabite, and Mayan populations.

The Washington State University and the University of Utah researchers said epigenetic variation may contribute to environmental adaptation in the birds.

When investigators retraced recurrent mutations, expression changes, and methylation shifts in hundreds of Wilms tumor case, they identified two main pathways.

The Belgian company recently received €3.6 million to develop the signature into a clinical test within the next three years.

Investigators identified changes in methylation at neurobiology-related genes when comparing blood methylation in twin pairs discordant for ALS.

Researchers identified shifts in regulatory features and enhanced NOTCH signaling pathway activation in prostate tumors containing a TMPRSS2-ERG2 gene fusion.

With exome sequences, RNA sequences, and methylation profiles, investigators uncovered differences between radiation-induced and sporadic forms of meningioma.

With mutation, expression, and epigenetic features from hundreds of medulloblastoma tumors, researchers characterized key features of brain tumor subtypes.

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Mainichi reports that 43 percent of Japanese individuals said they did not want to eat agricultural products that had been modified using gene-editing tools.

Two US Department of Agriculture research departments are moving to the Kansas City area, according to the Washington Post.

Slate's Jane Hu compares some at-home genetic tests to astrology.

In PLOS this week: analysis of polygenic risk scores for skin cancer, chronic pain GWAS, and more.