The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles.
The researchers used DNA methylation profiles to define 82 central nervous system tumor classes, some of which differed from WHO tumor classes.
The Epigenetics For Female Personalised Cancer Care (EpiFemCare) project recently published its findings in two papers in the journal Genome Medicine.
In Genome Biology this week: peopling of the Sahara, epigenetic reprogramming analysis of liverwort, and more.
A Dutch famine during World War II led to life-long epigenetic changes in individuals whose mothers were pregnant with them at the time.
Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.
A genomic analysis of ependymomas from 42 patients led to nearly 1,700 suspected super enhancers, highlighting potentially targetable genes.
Mount Sinai researchers have developed a metagenomic method based on PacBio sequencing that uses methylation patterns to identify species and their associated plasmids.
The firm has been developing several new tests that are based on its ADAPT aptamer profiling technology.
In PLOS this week: genetic variants associated with HIV infection risk, protein biomarkers of schistosomiasis, and more.
The chief executive of the National Health Service in England is to call for tumor-agnostic drugs to be "fast-tracked," according to the Times.
Researchers in Australia are sequencing the Wollemi pine tree to try to protect it from extinction, Australia's ABC News reports.
Computerworld ranks Illumina as one of the top midsize organizations to work at in IT.
In Genome Research this week: links between biological aging and mutations affecting epigenetic regulators; long-read sequencing-based strategy to map chromatin accessibility; and more.