The approach, called cfMeDIP-seq, could distinguish early-stage pancreatic cancer from healthy controls and differentiate several types of cancer.
Researchers found that methylation alterations affected immune response and lipid metabolism pathways in children whose growth had been stunted.
The team uncovered more than 200 sites in the human genome that were differentially methylated based on parent of origin, including areas linked to disease.
The firm plans to conduct a prospective trial of a pan cancer assay and aims to bring another assay focused on colorectal cancer through FDA clearance.
In Genome Biology this week: DNA methylation in soybean accessions, genetic ancestry of Uralic speakers, and more.
A team led by Walter and Eliza Hall Institute researchers found that ovarian tumors with complete BRCA1 methylation and silencing were more susceptible to treatment.
These differentially variable positions appear to implicate stress response in rheumatoid arthritis development and possibly in other autoimmune conditions.
In PNAS this week: history and genetic diversity of the scarlet macaw, approach for predicting human flu virus evolution, and more.
Researchers used array-based DNA methylation data to quantify methylation levels in almost 1,500 identical or non-identical twins.
The test uses changes in DNA methylation patterns for the early detection of lung cancer and is based on the same platform as the firm's bladder cancer test.
The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.
In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.
MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.
In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.