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methylation analysis

The Rehovot, Israel-based firm expects to soon receive marketing clearance from the US Food and Drug Administration for its methylation-based Bladder EpiCheck test.

In Genome Research this week: more than a dozen AML epitypes described, antisense RNA in vertebrate development, and more.

The Israeli-based startup will use the funds to continue development of its EpiCheck methylation platform and to develop the Lung EpiCheck assay.

In PLOS this week: DNA methylation patterns in breast cancer, multi-omic analysis of samples from COVID-19 patients, and more.

The approach applies deep learning and could potentially be used to identify people with early-stage disease when therapies may have more of an effect.

In Genome Biology this week: DNA methylation features found among neurodegenerative disorders, analysis of somatic variants in the brain, and more.

The results represent a significant improvement over currently used screening tools and are spurring renewed LDT commercialization and regulatory submission efforts.

In PLOS this week: analysis of DNA methylation in blood and epithelial cells, genomic analysis of Burkholderia multivorans isolates from cystic fibrosis patients, and more.

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.

A UCLA-led team uncovered differences in DNA methylation patterns between patients with persistent and resolving methicillin-resistant Staphylococcus aureus infections.

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The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.

According to the Associated Press, a Swiss program aims to shepherd long-term science projects and diplomacy.

CNN reports that two new studies suggest the B.1.1.7 SARS-CoV-2 variant may be more transmissible, but may not lead to more severe disease.

In PNAS this week: analysis of pathway affecting acute kidney injury, parental-specific allelic expression in horse placenta, and more.