GenomeWeb

methylation analysis

May 11, 2020

Genetic Ancestry Linked to Differences in Molecular Features of Cancers

A Broad Institute-led team found that differences by ancestry could affect not only how cancer develops but also treatment approaches.

Apr 30, 2020

Washington University, BostonGene Expand Kidney Cancer Research Collaboration

WUSTL will evaluate BostonGene's software, which integrates data from NGS with immunofluorescence imaging to profile tumors and their microenvironments.

Apr 24, 2020

Science Issues Expression of Concern Regarding Circulating Tumor DNA Methylation Paper, More

In Science this week: expression of concern issued for paper on using circulating tumor DNA methylation profiles to diagnose colorectal cancer, and more.

Apr 23, 2020

Elysium Health Licenses DNA Methylation Biomarkers From Yale University

The company markets anti-aging supplements and a direct-to-consumer DNA methylation analysis kit designed to provide information about biological age.

Apr 01, 2020

Genome Biology Papers Look at Neuronal Epigenetics in Parkinson's, Differential Expression Method, More

In Genome Biology this week: difference in methylation in neurons from Parkinson's disease patients, differential expression analysis by barcoded sequencing approach, and more.

Mar 09, 2020

Integrated Genomic Analysis Highlights Potential Strategy for Overcoming Some ALL Resistance

The study suggested that ALL glucocorticoid resistance stemming from alterations that drive down CELSR2 levels might be combated with the BCL2-targeting drug venetoclax.

Feb 20, 2020

DNA Methylation at Certain Sites May Have Causal Effect on Lung Function, Study Finds

The researchers' findings suggest that methylation at those sites might have their effect on lung function through its effect on smoking behaviors.

Feb 18, 2020

PNAS Papers Examine Prostate Cancer Splicing, Arabidopsis Methylation, X Chromosome Dosage Effects

In PNAS this week: role for Myc in alternative splicing regulation in prostate cancer, variation in methylation in Arabidopsis, and more.

Feb 04, 2020

PNAS Papers Look at Remethylation in DNMT3A-Deficient Setting, Glioblastoma Glycans, More

In PNAS this week: remethylation of DNMT3A in mice affects expansion of myeloid cells, glycan and receptor expression in glioblastoma, and more.

Jan 02, 2020

Circulating Tumor DNA Methylation Profiles May Aid in Colorectal Cancer Early Diagnosis, Prognosis

A Sun-Yat Sen University Cancer Center-led team found circulating tumor DNA methylation patterns could detect colorectal cancer among asymptomatic individuals.

Breaking News

The Scan

Preprints During Lockdown

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

ApoE and COVID-19

A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.

Search for Genetic Clues to COVID-19 Severity

Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.

PNAS Papers on Retinal Development, Adoptive T Cell Transfer, Blood Cell Differentiation

In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.

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