metagenomics

Gut microbiome researchers have identified features associated with everything from Crohn's disease to salt intake, immune activity, and hypertension.

A pair of papers point to potential gut microbial contributions to checkpoint blockade immunotherapy response in individuals with lung, kidney, or skin cancer.

At the recent IDWeek conference, company collaborators presented early validation data on a blood-based assay for cell-free microbial DNA.

People with atherosclerotic cardiovascular disease have increased levels of certain bacteria in their stool, a metagenome-wide association study has found.

The researchers plan to evaluate cfDNA and single cells isolated from the urine of patients who have had kidney transplants to identify signs of graft failure.

The firm has used its proximity ligation method to interpret metagenomic sequence data from a human fecal sample, unraveling new and known genomes in the mix. 

This Week in Nature

In Nature this week: Critical Assessment of Metagenome Interpretation results, and more.

The team tested 21 protocols for extracting DNA from human fecal microbiome samples to recommend one to improve comparability between studies.

Under an NIH grant, the firm plans to develop its Chicago method to analyze fecal metagenomic samples without relying on first culturing the bacteria.

Additional Human Microbiome Project samples have enabled a deeper look into the stability and molecular processes of the microbes that live on and in people.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.