massively parallel sequencing

Two separate studies concluded that in most SEO cancer cases what they are seeing are two separate early-stage tumors, instead of late-stage cancer.

During a panel discussion at Cambridge Healthtech Institute's Advances in Prenatal Molecular Diagnostics conference in Boston earlier this month, representatives from four NIPT providers - Ariosa Diagnostics, Natera, Sequenom, and Illumina - shared their vision for their own tests and the future of NIPT.

Researchers from Radboud University Nijmegen Medical Center have published a method of non-invasive prenatal diagnosis using massively parallel sequencing-by-ligation on the Life Technologies SOLiD 4 platform.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – A gene fusion identified in DNA and RNA sequences from a never-smoker lung cancer patient may act as a driver in a subset of lung cancer cases, a new study suggests.

The method, dubbed single-tube linear DNA amplification, or LinDA, is expected to facilitate genome-wide profiling of transcription factors and chromatin analyses using DNA obtained from just a few hundred cells.

At the American Society of Clinical Oncology annual meeting yesterday, Nikhil Wagle described a multiplexed approach for identifying mutations in nearly 140 cancer-related genes.

Using an RNA interference screen that relies on massively parallel sequencing, British researchers have identified new genes that seem to contribute to sensitivity or resistance to the breast cancer drug tamoxifen.

By sequencing a tumor from a mouse model of acute promyelocytic leukemia, researchers from Washington University have identified mutations that overlap with those detected in human forms of the disease.

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The president of France's National Research Agency has resigned, according to Nature News.

A senator wants a "right-to-try" provision in the US Food and Drug Administration funding bill, but an ethicist says at Stat News that it would undermine the role of clinical trials.

In PNAS this week: red algae Porphyra umbicalis genome, deep neural network model for sequencing peptides, and more.

The Guardian's Barbara Ellen has tried out some DNA testing services to see whether they provide valuable information.