massively parallel sequencing

Two separate studies concluded that in most SEO cancer cases what they are seeing are two separate early-stage tumors, instead of late-stage cancer.

During a panel discussion at Cambridge Healthtech Institute's Advances in Prenatal Molecular Diagnostics conference in Boston earlier this month, representatives from four NIPT providers - Ariosa Diagnostics, Natera, Sequenom, and Illumina - shared their vision for their own tests and the future of NIPT.

Researchers from Radboud University Nijmegen Medical Center have published a method of non-invasive prenatal diagnosis using massively parallel sequencing-by-ligation on the Life Technologies SOLiD 4 platform.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – A gene fusion identified in DNA and RNA sequences from a never-smoker lung cancer patient may act as a driver in a subset of lung cancer cases, a new study suggests.

The method, dubbed single-tube linear DNA amplification, or LinDA, is expected to facilitate genome-wide profiling of transcription factors and chromatin analyses using DNA obtained from just a few hundred cells.

At the American Society of Clinical Oncology annual meeting yesterday, Nikhil Wagle described a multiplexed approach for identifying mutations in nearly 140 cancer-related genes.

Using an RNA interference screen that relies on massively parallel sequencing, British researchers have identified new genes that seem to contribute to sensitivity or resistance to the breast cancer drug tamoxifen.

By sequencing a tumor from a mouse model of acute promyelocytic leukemia, researchers from Washington University have identified mutations that overlap with those detected in human forms of the disease.

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New results from the NASA Twins Study indicate that the immune system may rev up when in space, the Washington Post reports.

Kelvin Droegemeier, the new science advisor, spoke at the American Association for the Advancement of Science meeting, Geekwire reports.

In PNAS this week: whole-genome assembly for the white shark, paper-based microfluidic method for detecting the malaria parasite, and more.

The World Health Organization has announced the members of its gene-editing committee, according to NPR.